SX-576

Modify Date: 2024-09-08 17:44:02

SX-576 Structure
SX-576 structure
Common Name SX-576
CAS Number 1240494-14-7 Molecular Weight 466.214
Density N/A Boiling Point N/A
Molecular Formula C20H15BF4N2O4S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of SX-576


A potent, equipotent CXCR1 and CXCR2 antagonist with IC50 of 31 nM and 21 nM, respectively; exhibits potent inhibition of neutrophil influx in rat model of pulmonary inflammation.

 Names

Name SX-576

 SX-576 Biological Activity

Description A potent, equipotent CXCR1 and CXCR2 antagonist with IC50 of 31 nM and 21 nM, respectively; exhibits potent inhibition of neutrophil influx in rat model of pulmonary inflammation.
References References 1. Maeda DY, et al. Bioorg Med Chem Lett. 2015 Jun 1;25(11):2280-4. 2. Schuler AD, et al. Bioorg Med Chem Lett. 2015 Sep 15;25(18):3793-7. View Related Products by Target Chemokine Receptor (CCR and CXCR)

 Chemical & Physical Properties

Molecular Formula C20H15BF4N2O4S
Molecular Weight 466.214
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