SX-576

Names

[ Name ]:
SX-576

Biological Activity

[Description]:

A potent, equipotent CXCR1 and CXCR2 antagonist with IC50 of 31 nM and 21 nM, respectively; exhibits potent inhibition of neutrophil influx in rat model of pulmonary inflammation.

[References]

References 1. Maeda DY, et al. Bioorg Med Chem Lett. 2015 Jun 1;25(11):2280-4. 2. Schuler AD, et al. Bioorg Med Chem Lett. 2015 Sep 15;25(18):3793-7. View Related Products by Target Chemokine Receptor (CCR and CXCR)

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₀H₁₅BF₄N₂O₄S

[ Molecular Weight ]:
466.214

Related Compounds

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