Sabutoclax
Modify Date: 2024-01-05 09:16:11
Sabutoclax structure
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Common Name | Sabutoclax | ||
|---|---|---|---|---|
| CAS Number | 1228108-65-3 | Molecular Weight | 700.776 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 905.9±65.0 °C at 760 mmHg | |
| Molecular Formula | C42H40N2O8 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 501.7±34.3 °C | |
Use of SabutoclaxSabutoclax is a potent and effective Bcl-2 Family (Bcl-2, Bcl-XL, Mcl-1, Bfl-1) inhibitor with IC50s of 0.32 μM, 0.31 μM, 0.20 μM, and 0.62 μM, respectively. |
| Name | 2,3,5-trihydroxy-7-methyl-N-[(2R)-2-phenylpropyl]-6-[1,6,7-trihydroxy-3-methyl-5-[[(2R)-2-phenylpropyl]carbamoyl]naphthalen-2-yl]naphthalene-1-carboxamide |
|---|---|
| Synonym | More Synonyms |
| Description | Sabutoclax is a potent and effective Bcl-2 Family (Bcl-2, Bcl-XL, Mcl-1, Bfl-1) inhibitor with IC50s of 0.32 μM, 0.31 μM, 0.20 μM, and 0.62 μM, respectively. |
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| Related Catalog | |
| Target |
Bcl-xL:0.31 μM (IC50) BCL2:0.32 μM (IC50) Mcl-1:0.2 μM (IC50) Bfl-1:0.62 μM (IC50) |
| References |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 905.9±65.0 °C at 760 mmHg |
| Molecular Formula | C42H40N2O8 |
| Molecular Weight | 700.776 |
| Flash Point | 501.7±34.3 °C |
| Exact Mass | 700.278442 |
| PSA | 186.56000 |
| LogP | 7.47 |
| Vapour Pressure | 0.0±0.3 mmHg at 25°C |
| Index of Refraction | 1.713 |
| Storage condition | -20℃ |
| 1,1',6,6',7,7'-hexahydroxy-3,3'-dimethyl-N5,N5'-bis(2-phenylpropyl)-2,2'-binaphthyl-5,5'-dicarboxamide |
| [2,2'-Binaphthalene]-5,5'-dicarboxamide, 1,1',6,6',7,7'-hexahydroxy-3,3'-dimethyl-N,N-bis[(2R)-2-phenylpropyl]- |
| UNII:39Y89ZRK34 |
| 1,1',6,6',7,7'-HEXAHYDROXY-3,3'-DIMETHYL-N5-((R)-2-PHENYLPROPYL)-N5'-((R)-2-PHENYLPROPYL)-2,2'-BINAPHTHYL-5,5'-DICARBOXAMIDE (ATROPISOMERIC MIX) |
| Sabutoclax |
| UNII-39Y89ZRK34 |
| 1,1',6,6',7,7'-Hexahydroxy-3,3'-dimethyl-N,N'-bis[(2R)-2-phenylpropyl]-2,2'-binaphthalene-5,5'-dicarboxamide |
| BI-97C1 |