JW-7-25-1
Modify Date: 2025-08-25 12:41:28
JW-7-25-1 structure
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Common Name | JW-7-25-1 | ||
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| CAS Number | 1222998-57-3 | Molecular Weight | 516.524 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C29H23F3N4O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of JW-7-25-1JW-7-25-1 is a potent MELK inhibitor with biochemical IC50 of 5.0 nM, also inhibits PIK3CA, mTOR, GSK3A and CDK7 with CI50 of 5-60 nM; exhibits a broad kinase selectivity profile with an S(35) score of 0.54 at 10 uM. |
| Name | JW-7-25-1 |
|---|
| Description | JW-7-25-1 is a potent MELK inhibitor with biochemical IC50 of 5.0 nM, also inhibits PIK3CA, mTOR, GSK3A and CDK7 with CI50 of 5-60 nM; exhibits a broad kinase selectivity profile with an S(35) score of 0.54 at 10 uM. |
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| References | References 1. Huang HT, et al. Elife. 2017 Sep 19;6. pii: e26693. View Related Products by Target MELK |
| Molecular Formula | C29H23F3N4O2 |
|---|---|
| Molecular Weight | 516.524 |