Trichostatin A S-isomer
Modify Date: 2024-01-17 21:08:49
Trichostatin A S-isomer structure
|
Common Name | Trichostatin A S-isomer | ||
|---|---|---|---|---|
| CAS Number | 122292-85-7 | Molecular Weight | 302.36800 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C17H22N2O3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
| Name | Trichostatin A |
|---|---|
| Synonym | More Synonyms |
| Description | (S)-Trichostatin A ((S)-TSA) 是一种 HDAC6 选择性抑制剂，对斑马鱼 HDAC6 和人 HDAC6 的 IC50 值分别为 9.88 nM和 11.1 nM。(S)-Trichostatin A 弱抑制其他人 HDAC。 |
|---|---|
| Related Catalog | |
| Target |
hHDAC6:11.1 nM (IC50) Zebrafish HDAC6:9.88 nM (IC50) hHDAC1:206.3 nM (IC50) hHDAC2:612.65 nM (IC50) hHDAC3:320.8 nM (IC50) hHDAC4:6341 nM (IC50) hHDAC5:6325 nM (IC50) hHDAC7:1823.5 nM (IC50) hHDAC8:312.2 nM (IC50) hHDAC9:4824 nM (IC50) hHDAC10:403.35 nM (IC50) hHDAC11:2684 nM (IC50) |
| References |
| Molecular Formula | C17H22N2O3 |
|---|---|
| Molecular Weight | 302.36800 |
| Exact Mass | 302.16300 |
| PSA | 69.64000 |
| LogP | 2.97020 |
|
~%
Trichostatin A ... CAS#:122292-85-7 |
| Literature: Mori, Kenji; Koseki, Koshi Tetrahedron, 1988 , vol. 44, # 19 p. 6013 - 6020 |
|
~%
Trichostatin A ... CAS#:122292-85-7 |
| Literature: Mori, Kenji; Koseki, Koshi Tetrahedron, 1988 , vol. 44, # 19 p. 6013 - 6020 |
| Precursor 2 | |
|---|---|
| DownStream 0 | |
| .TSA |
| .(R)-trichostatin A |
| .(R)-(+)-trichostatin A |
| .(7-[4-(dimethylamino)phenyl]-N-hydroxy-4,6-dimethyl-7-oxohepta-2,4-dienamide) |
| (+)-TSA |