CSIC E379
Modify Date: 2024-09-14 09:29:28
CSIC E379 structure
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Common Name | CSIC E379 | ||
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| CAS Number | 1220476-13-0 | Molecular Weight | 280.411 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C20H24O | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of CSIC E379CSIC E379 is a potent, selective uncoupling proteins UCP1/UCP2 inhibitor with EC50 of 20 uM/30 uM, respectively; does not affect OXPHOS system and membrane permeability in liver mitochondria; causes oxidative stress, inhibit the cellular respiration of the cancer cell line HT-29; increases the production of superoxide and decreases the cell viability; potentiates the efficacy of the cytotoxic drug arsenic trioxide. |
| Name | CSIC E379 |
|---|
| Description | CSIC E379 is a potent, selective uncoupling proteins UCP1/UCP2 inhibitor with EC50 of 20 uM/30 uM, respectively; does not affect OXPHOS system and membrane permeability in liver mitochondria; causes oxidative stress, inhibit the cellular respiration of the cancer cell line HT-29; increases the production of superoxide and decreases the cell viability; potentiates the efficacy of the cytotoxic drug arsenic trioxide. |
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| References | References 1. Rial E, et al. Chem Biol. 2011 Feb 25;18(2):264-74. View Related Products by Target Other Targets |
| Molecular Formula | C20H24O |
|---|---|
| Molecular Weight | 280.411 |