(-)-Ibuprofenamide

Modify Date: 2024-01-09 16:38:25

(-)-Ibuprofenamide Structure
(-)-Ibuprofenamide structure
Common Name (-)-Ibuprofenamide
CAS Number 121839-78-9 Molecular Weight 205.30
Density N/A Boiling Point N/A
Molecular Formula C13H19NO Melting Point N/A
MSDS N/A Flash Point N/A

 Use of (-)-Ibuprofenamide


(-)-Ibuprofenamide is an amide prodrug of Ibuprofen with anti-inflammatory activity[1]. Ibuprofen is an anti-inflammatory inhibitor targeting COX-1 and COX-2 with IC50s of 13 μM and 370 μM, respectively[2].

 Names

Name (2R)-2-[4-(2-methylpropyl)phenyl]propanamide
Synonym More Synonyms

 (-)-Ibuprofenamide Biological Activity

Description (-)-Ibuprofenamide is an amide prodrug of Ibuprofen with anti-inflammatory activity[1]. Ibuprofen is an anti-inflammatory inhibitor targeting COX-1 and COX-2 with IC50s of 13 μM and 370 μM, respectively[2].
Related Catalog
Target

COX-1, COX-2[2]

References

[1]. Shanbhag VR, et al. Ester and amide prodrugs of ibuprofen and naproxen: synthesis, anti-inflammatory activity, and gastrointestinal toxicity. J Pharm Sci. 1992 Feb;81(2):149-54.

[2]. Noreen Y, et al. Development of a radiochemical cyclooxygenase-1 and -2 in vitro assay for identification of natural products as inhibitors of prostaglandin biosynthesis. J Nat Prod. 1998 Jan;61(1):2-7.

 Chemical & Physical Properties

Molecular Formula C13H19NO
Molecular Weight 205.30
Exact Mass 205.14700
PSA 43.09000
LogP 3.17420

 Synonyms

(R)-2-(4-Isobutyl-phenyl)-propionamide
(R)-2-(4-isobutylphenyl)propionamide
Top Suppliers:I want be here

No recommended suppliers.

Hot Compounds More...
Dichloromethane
CAS#:75-09-2
Polyacrylic acid
CAS#:9003-01-4
sodium carbonate
CAS#:497-19-8
Silicon dioxide
CAS#:7631-86-9
Triethanolamine
CAS#:102-71-6
Demeton
CAS#:126-75-0
Water
CAS#:7732-18-5
4-(4-Piperidinyl)morpholine dihydrochloride
CAS#:53617-35-9
Diclofenac sodium
CAS#:15307-79-6
Budesonide
CAS#:51372-29-3