Desmethyl Levofloxacin-d8

Modify Date: 2024-01-09 12:16:26

Desmethyl Levofloxacin-d8 Structure
Desmethyl Levofloxacin-d8 structure
Common Name Desmethyl Levofloxacin-d8
CAS Number 1217976-18-5 Molecular Weight 355.39
Density N/A Boiling Point N/A
Molecular Formula C17H10D8FN3O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Desmethyl Levofloxacin-d8


Desmethyl Levofloxacin-d8 is deuterium labeled Desmethyl Levofloxacin. Desmethyl Levofloxacin is a metabolite of Levofloxacin. Levofloxacin, a synthetic fluoroquinolone, is an antibacterial agent that inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication[1].

 Names

Name Desmethyl Levofloxacin-d8

 Desmethyl Levofloxacin-d8 Biological Activity

Description Desmethyl Levofloxacin-d8 is deuterium labeled Desmethyl Levofloxacin. Desmethyl Levofloxacin is a metabolite of Levofloxacin. Levofloxacin, a synthetic fluoroquinolone, is an antibacterial agent that inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication[1].
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

[2]. Siva, R., et al., Effect of levofloxacin on neutrophilic airway inflammation in stable COPD: a randomized, double-blind, placebo-controlled trial. Int J Chron Obstruct Pulmon Dis, 2014. 9: p. 179-86.

 Chemical & Physical Properties

Molecular Formula C17H10D8FN3O4
Molecular Weight 355.39