rac Fosfomycin-13C3 Benzylamine Salt

Modify Date: 2024-04-06 17:59:11

rac Fosfomycin-13C3 Benzylamine Salt Structure
rac Fosfomycin-13C3 Benzylamine Salt structure
Common Name rac Fosfomycin-13C3 Benzylamine Salt
CAS Number 1216461-18-5 Molecular Weight 248.239101
Density N/A Boiling Point N/A
Molecular Formula C10H16NO4P Melting Point N/A
MSDS N/A Flash Point N/A

 Use of rac Fosfomycin-13C3 Benzylamine Salt


(Rac)-Fosfomycin (benzylamine)-13C3 is the 13C labeled Fosfomycin[1]. Fosfomycin (MK-0955) is a broad-spectrum antibiotic. Fosfomycin can cross blood-brain barrier penetrating, and irreversibly inhibits an early stage in cell wall synthesis. Fosfomycin shows anti-bacteria activity for a range of bacteria, including multidrug-resistant (MDR), extensively drug-resistant (XDR), and pan-drug-resistant (PDR) bacteria[2][3].

 Names

Name yfochwjdruxoiq-burviegvsa-n

 rac Fosfomycin-13C3 Benzylamine Salt Biological Activity

Description (Rac)-Fosfomycin (benzylamine)-13C3 is the 13C labeled Fosfomycin[1]. Fosfomycin (MK-0955) is a broad-spectrum antibiotic. Fosfomycin can cross blood-brain barrier penetrating, and irreversibly inhibits an early stage in cell wall synthesis. Fosfomycin shows anti-bacteria activity for a range of bacteria, including multidrug-resistant (MDR), extensively drug-resistant (XDR), and pan-drug-resistant (PDR) bacteria[2][3].
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

[2]. Falagas ME, et al. Fosfomycin. Clin Microbiol Rev. 2016 Apr. 29(2):321-47.  

[3]. Dijkmans AC, et al. Fosfomycin: Pharmacological, Clinical and Future Perspectives. Antibiotics (Basel). 2017 Oct 31. 6(4):24.  

[4]. Inouye S, et al. Mode of protective action of fosfomycin against dibekacin-induced nephrotoxicity in the dehydrated rats. J Pharmacobiodyn. 1982 Dec. 5(12):941-50.  

 Chemical & Physical Properties

Molecular Formula C10H16NO4P
Molecular Weight 248.239101
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