2-Methoxy-3-(trifluoromethyl)pyridine

Modify Date: 2024-01-02 12:31:55

2-Methoxy-3-(trifluoromethyl)pyridine Structure
2-Methoxy-3-(trifluoromethyl)pyridine structure
Common Name 2-Methoxy-3-(trifluoromethyl)pyridine
CAS Number 121643-44-5 Molecular Weight 177.124
Density 1.3±0.1 g/cm3 Boiling Point 172.9±40.0 °C at 760 mmHg
Molecular Formula C7H6F3NO Melting Point N/A
MSDS Chinese USA Flash Point 58.4±27.3 °C
Symbol GHS02 GHS06
GHS02, GHS06
Signal Word Danger

 Names

Name 2-Methoxy-3-(trifluoromethyl)pyridine
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 172.9±40.0 °C at 760 mmHg
Molecular Formula C7H6F3NO
Molecular Weight 177.124
Flash Point 58.4±27.3 °C
Exact Mass 177.040146
PSA 22.12000
LogP 2.76
Vapour Pressure 1.7±0.3 mmHg at 25°C
Index of Refraction 1.427

 Safety Information

Symbol GHS02 GHS06
GHS02, GHS06
Signal Word Danger
Hazard Statements H226-H300-H315-H319-H335
Precautionary Statements P261-P264-P301 + P310-P305 + P351 + P338
Personal Protective Equipment Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes T:Toxic;
Risk Phrases R10;R25;R36/37/38
Safety Phrases S16-S26-S45
RIDADR UN 1992 3/PG 3
WGK Germany 3

 Synthetic Route

~91%

2-Methoxy-3-(trifluoromethyl)pyridine Structure

2-Methoxy-3-(tr...

CAS#:121643-44-5

Literature: NOVARTIS AG; COOKE, Nigel Graham; FERNANDES GOMES DOS SANTOS, Paulo Antonio; FURET, Pascal; HEBACH, Christina; HÖGENAUER, Klemens; HOLLINGWORTH, Gregory; KALIS, Christoph; LEWIS, Ian; SMITH, Alexander Baxter; SOLDERMANN, Nicolas; STAUFFER, Frédéric; STRANG, Ross; STOWASSER, Frank; TUFILLI, Nicola; VON MATT, Anette; WOLF, Romain; ZECRI, Frédéric Patent: WO2013/88404 A1, 2013 ; Location in patent: Page/Page column 92 ;

~98%

2-Methoxy-3-(trifluoromethyl)pyridine Structure

2-Methoxy-3-(tr...

CAS#:121643-44-5

Literature: Ye, Yingda; Kuenzi, Stefan A.; Sanford, Melanie S. Organic Letters, 2012 , vol. 14, # 19 p. 4979 - 4981,3 Title/Abstract Full Text Show Details Ye, Yingda; Kuenzi, Stefan A.; Sanford, Melanie S. Organic Letters, 2012 , vol. 14, # 19 p. 4979 - 4981

~%

2-Methoxy-3-(trifluoromethyl)pyridine Structure

2-Methoxy-3-(tr...

CAS#:121643-44-5

Literature: WO2006/42289 A2, ; Page/Page column 51 ;

~69%

2-Methoxy-3-(trifluoromethyl)pyridine Structure

2-Methoxy-3-(tr...

CAS#:121643-44-5

Literature: Dainter, Ronald S.; Jackson, Tracey; Omar, Abdirahman H. H.; Suschitzky, Hans; Wakefield, Basil J.; et al. Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1989 , p. 283 - 287

 Synonyms

2-methoxy-3-trifluoromethyl-pyridine
2-Methoxy-3-(trifluoromethyl)pyridine
2-Methoxy-3-Trifluoromethylpyridine
Pyridine, 2-methoxy-3-(trifluoromethyl)-
MFCD00153202