2-AMINO-5-NITROPENOL

Modify Date: 2024-01-02 13:08:58

2-AMINO-5-NITROPENOL Structure
2-AMINO-5-NITROPENOL structure
Common Name 2-AMINO-5-NITROPENOL
CAS Number 121-88-0 Molecular Weight 154.123
Density 1.5±0.1 g/cm3 Boiling Point 364.0±32.0 °C at 760 mmHg
Molecular Formula C6H6N2O3 Melting Point 198-202 °C (dec.)(lit.)
MSDS Chinese USA Flash Point 173.9±25.1 °C
Symbol GHS07
GHS07
Signal Word Warning

 Names

Name 2-Amino-5-nitrophenol
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.5±0.1 g/cm3
Boiling Point 364.0±32.0 °C at 760 mmHg
Melting Point 198-202 °C (dec.)(lit.)
Molecular Formula C6H6N2O3
Molecular Weight 154.123
Flash Point 173.9±25.1 °C
Exact Mass 154.037842
PSA 92.07000
LogP 1.61
Vapour Pressure 0.0±0.8 mmHg at 25°C
Index of Refraction 1.689
Water Solubility insoluble

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
SJ6302500
CHEMICAL NAME :
Phenol, 2-amino-5-nitro-
CAS REGISTRY NUMBER :
121-88-0
BEILSTEIN REFERENCE NO. :
0972974
LAST UPDATED :
199710
DATA ITEMS CITED :
23
MOLECULAR FORMULA :
C6-H6-N2-O3
MOLECULAR WEIGHT :
154.14
WISWESSER LINE NOTATION :
ZR BQ DNW

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>4 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>800 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
3756 mg/kg/16D-I
TOXIC EFFECTS :
Related to Chronic Data - death
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
52 gm/kg/13W-I
TOXIC EFFECTS :
Gastrointestinal - ulceration or bleeding from large intestine Liver - changes in liver weight Related to Chronic Data - death
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
7500 mg/kg/16D-I
TOXIC EFFECTS :
Related to Chronic Data - death
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
104 gm/kg/13W-I
TOXIC EFFECTS :
Liver - changes in liver weight Related to Chronic Data - death
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
51500 mg/kg/2Y-C
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria Gastrointestinal - tumors

MUTATION DATA

TYPE OF TEST :
Sister chromatid exchange
TEST SYSTEM :
Rodent - hamster Ovary
DOSE/DURATION :
1240 mg/L
REFERENCE :
NTPTR* National Toxicology Program Technical Report Series. (Research Triangle Park, NC 27709) No.206- Volume(issue)/page/year: NTP-TR-334,1988 *** REVIEWS *** IARC Cancer Review:Animal Limited Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 57,177,1993 IARC Cancer Review:Human Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 57,177,1993 IARC Cancer Review:Group 3 IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 57,177,1993 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X1660 No. of Facilities: 1339 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 14512 (estimated) No. of Female Employees: 11827 (estimated)

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xn:Harmful
Risk Phrases R36/37/38;R68
Safety Phrases S26-S36/37-S45-S36/37/39
RIDADR 2811
WGK Germany 2
RTECS SJ6302500
HS Code 2922299090

 Synthetic Route

 Customs

HS Code 2922299090
Summary 2922299090. other amino-naphthols and other amino-phenols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

 Articles7

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 Synonyms

2-amino-5-nitro-pheno
Phenol, 2-amino-5-nitro-
3-nitro-6-aminophenol
2-Amino-5-nirtophenol
EINECS 204-503-8
3-hydroxy-4-aminonitrobenzene
4-amino-3-hydroxynitrobenzene
5-nitro-2-aminophenol
1-amino-2-hydroxy-4-nitrobenzene
ursolyellowbrowna
1-hydroxy-2-amino-5-nitrobenzene
2-AMINO-5-NITROPENOL
2-Amino-5-nitro-phenol
2-hydroxy 4-nitro aniline
rodolyba
2-Hydroxy-4-nitroaniline
MFCD00007692
2-Amino-5-nitrophenol
5-nitro-2-amino-1-hydroxybenzene