SRT3109
Modify Date: 2025-08-24 11:23:06
SRT3109 structure
|
Common Name | SRT3109 | ||
|---|---|---|---|---|
| CAS Number | 1204707-71-0 | Molecular Weight | 475.533 | |
| Density | 1.6±0.1 g/cm3 | Boiling Point | 726.6±70.0 °C at 760 mmHg | |
| Molecular Formula | C18H23F2N5O4S2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 393.3±35.7 °C | |
Use of SRT3109SRT3109 is an antagonist of CXCR2, with a pIC50 of 8.2, and used in the research of chemokine mediated diseases. |
| Name | N-[2-[(2,3-difluorophenyl)methylsulfanyl]-6-[[(2R,3R)-3,4-dihydroxybutan-2-yl]amino]pyrimidin-4-yl]azetidine-1-sulfonamide |
|---|---|
| Synonym | More Synonyms |
| Description | SRT3109 is an antagonist of CXCR2, with a pIC50 of 8.2, and used in the research of chemokine mediated diseases. |
|---|---|
| Related Catalog | |
| Target |
CXCR2:8.2 (pIC50) |
| In Vitro | SRT3109 (Example 1) is an antagonist of CXCR2, with a pIC50 of 8.2, and used in the research of chemokine mediated diseases[1]. |
| References |
| Density | 1.6±0.1 g/cm3 |
|---|---|
| Boiling Point | 726.6±70.0 °C at 760 mmHg |
| Molecular Formula | C18H23F2N5O4S2 |
| Molecular Weight | 475.533 |
| Flash Point | 393.3±35.7 °C |
| Exact Mass | 475.115936 |
| PSA | 161.36000 |
| LogP | 2.07 |
| Vapour Pressure | 0.0±2.5 mmHg at 25°C |
| Index of Refraction | 1.661 |
| Storage condition | 2-8℃ |
|
~62%
SRT3109 CAS#:1204707-71-0 |
| Literature: MEGHANI, PREMJI; ROBBINS, ANDREW JAMES; STONEHOUSE, JEFFREY PAUL Patent: US2010/16275 A1, 2010 ; Location in patent: Page/Page column 12 ; |
|
~64%
SRT3109 CAS#:1204707-71-0 |
| Literature: MEGHANI, PREMJI; ROBBINS, ANDREW JAMES; STONEHOUSE, JEFFREY PAUL Patent: US2010/16275 A1, 2010 ; Location in patent: Page/Page column 14 ; |
![(2R,3R)-3-({6-chloro-2-[(2,3-difluorobenzyl)thio]pyrimidin-4-yl}amino)butane-1,2-diol structure](https://image.chemsrc.com/caspic/355/1204707-78-7.png)
![N-[2-[(2,3-difluorobenzyl)thio]-6-({(1R)-1-[(4R)-2,2-dimethyl-1,3-dioxolan-4-yl]ethyl}amino)pyrimidin-4-yl]azetidine-1-sulfonamide structure](https://image.chemsrc.com/caspic/414/1204707-81-2.png)
| Precursor 3 | |
|---|---|
| DownStream 0 | |
| Y0301 |
| CS-0977 |
| 1-Azetidinesulfonamide, N-[2-[[(2,3-difluorophenyl)methyl]thio]-6-[[(1R,2R)-2,3-dihydroxy-1-methylpropyl]amino]-4-pyrimidinyl]- |
| SRT-3109 |
| cc-200 |
| N-(2-[(2,3-Difluorobenzyl)sulfanyl]-6-{[(2R,3R)-3,4-dihydroxy-2-butanyl]amino}-4-pyrimidinyl)-1-azetidinesulfonamide |
| SRT3109 |