SDZ CO 611

Modify Date: 2024-01-02 19:04:44

SDZ CO 611 Structure
SDZ CO 611 structure
Common Name SDZ CO 611
CAS Number 119719-11-8 Molecular Weight 1343.521
Density 1.5±0.1 g/cm3 Boiling Point 1665.9±65.0 °C at 760 mmHg
Molecular Formula C61H86N10O20S2 Melting Point N/A
MSDS N/A Flash Point 961.3±34.3 °C

 Use of SDZ CO 611


Ilatreotide (SDZ CO61), glycated somatostatin derivative, is a highly potent glycated analog of somatostatin with improved oral activity. Ilatreotide can suppress the fasting level and postprandial release of several gastrointestinal and pancreatic hormones. Ilatreotide can be used for the research of gastroenteropancreatic tumors[1][2][3].

 Names

Name Ilatreotide
Synonym More Synonyms

 SDZ CO 611 Biological Activity

Description Ilatreotide (SDZ CO61), glycated somatostatin derivative, is a highly potent glycated analog of somatostatin with improved oral activity. Ilatreotide can suppress the fasting level and postprandial release of several gastrointestinal and pancreatic hormones. Ilatreotide can be used for the research of gastroenteropancreatic tumors[1][2][3].
Related Catalog
References

[1]. Drum, et al. Use of somatostatin analogs in myocardial perfusion imaging. Patent. WO2008143958 A1.

[2]. Albert R,et al. SDZ CO 611: a highly potent glycated analog of somatostatin with improved oral activity. Life Sci. 1993;53(6):517-25.  

[3]. Nelson-Piercy C, et al. Effect of a new oral somatostatin analog (SDZ CO 611) on gastric emptying, mouth to cecum transit time, and pancreatic and gut hormone release in normal male subjects. J Clin Endocrinol Metab. 1994 Feb;78(2):329-36.  

 Chemical & Physical Properties

Density 1.5±0.1 g/cm3
Boiling Point 1665.9±65.0 °C at 760 mmHg
Molecular Formula C61H86N10O20S2
Molecular Weight 1343.521
Flash Point 961.3±34.3 °C
Exact Mass 1342.546143
LogP -1.41
Vapour Pressure 0.0±0.3 mmHg at 25°C
Index of Refraction 1.693

 Synonyms

β-D-fructopyranose, 1-[[(1R)-2-[[(4R,7S,10S,13R,16S,19R)-10-(4-aminobutyl)-7-[(1R)-1-hydroxyethyl]-4-[[[(1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl]amino]carbonyl]-13-(1H-indol-3-ylmethyl)-6,9,12,15,18-pentaoxo-16-(phenylmethyl)-1,2-dithia-5,8,11,14,17-pentaazacycloeicos-19-yl]amino]-2-oxo-1-(phenylmethyl)ethyl]amino]-1-deoxy-4-O-α-D-glucopyranosyl-
β-D-Fructopyranose, 1-[[(1R)-2-[[(4R,7S,10S,13R,16S,19R)-10-(4-aminobutyl)-7-[(1R)-1-hydroxyethyl]-4-[[[(1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl]amino]carbonyl]-13-(1H-indol-3-ylmethyl)-6,9,12,15, 18-pentaoxo-16-(phenylmethyl)-1,2-dithia-5,8,11,14,17-pentaazacycloeicos-19-yl]amino]-2-oxo-1-(phenylmethyl)ethyl]amino]-1-deoxy-4-O-α-D-glucopyranosyl-
Ilatreotide
(4R,7S,10S,13R,16S,19R)-10-(4-Aminobutyl)-16-benzyl-N-[(2R,3R)-1,3-dihydroxy-2-butanyl]-7-[(1R)-1-hydroxyethyl]-13-(1H-indol-3-ylmethyl)-6,9,12,15,18-pentaoxo-19-{[(2R)-3-phenyl-2-({[(2R,3S,4R,5R)-2,3,5-trihydroxy-4-{[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}tetrahydro-2H-pyran-2-yl]methyl}amino)propanoyl]amino}-1,2-dithia-5,8,11,14,17-pentaazacycloicosane-4-carboxamide
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