ST-1006 Maleate
Modify Date: 2025-08-25 23:42:25
ST-1006 Maleate structure
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Common Name | ST-1006 Maleate | ||
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| CAS Number | 1196994-12-3 | Molecular Weight | 599.42 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C24H28Cl2N6O8 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of ST-1006 MaleateST-1006 maleate is a potent histamine H4 receptor agonist with a pKi value of 7.94. ST-1006 maleate has anti-inflammatory effect[1][2]. |
| Name | ST-1006 Maleate |
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| Description | ST-1006 maleate is a potent histamine H4 receptor agonist with a pKi value of 7.94. ST-1006 maleate has anti-inflammatory effect[1][2]. |
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| Related Catalog | |
| In Vitro | ST-1006 (10 μM) maleate is a potent inducer of basophil migration and induces migration of basophils[2]. ST-1006 (0-100 μM) maleate suppress FceRImediated basophil activation and reduces the CD63 and CD203c expression levels on FceRI-activated basophils[2]. |
| In Vivo | ST-1006 (1-100 mg/kg; s.c.; Male CD-1 mice) maleate has anti-inflammatory effect and displays an antipruritic effect[1]. Animal Model: Male CD-1 mice with pruritus (8-10 weeks and 25-30 g)[1] Dosage: 1-100 mg/kg Administration: Subcutaneous injection Result: Had an antipruritic effect at the non-anti-inflammatory dose of 30 mg/kg. |
| References |
| Molecular Formula | C24H28Cl2N6O8 |
|---|---|
| Molecular Weight | 599.42 |
| InChIKey | NBLGNUAWAKUPSY-SPIKMXEPSA-N |
| SMILES | CN1CCN(c2cc(NCc3c(Cl)cccc3Cl)nc(N)n2)CC1.O=C(O)C=CC(=O)O.O=C(O)C=CC(=O)O |