6-O-Methyl-2',4''-bis-O-(trimethylsilyl)-9-[O-(1-ethoxy-1-methylethyl)oxime]-Erythromycin

Modify Date: 2024-01-03 19:14:36

6-O-Methyl-2',4''-bis-O-(trimethylsilyl)-9-[O-(1-ethoxy-1-methylethyl)oxime]-Erythromycin structure	Common Name	6-O-Methyl-2',4''-bis-O-(trimethylsilyl)-9-[O-(1-ethoxy-1-methylethyl)oxime]-Erythromycin
	CAS Number	119665-62-2	Molecular Weight	993.463
	Density	1.1±0.1 g/cm3	Boiling Point	838.4±75.0 °C at 760 mmHg
	Molecular Formula	C₄₉H₉₆N₂O₁₄Si₂	Melting Point	N/A
	MSDS	N/A	Flash Point	460.9±37.1 °C

Name	Intermediate of Clarithromycin
Synonym	More Synonyms

Density	1.1±0.1 g/cm3
Boiling Point	838.4±75.0 °C at 760 mmHg
Molecular Formula	C₄₉H₉₆N₂O₁₄Si₂
Molecular Weight	993.463
Flash Point	460.9±37.1 °C
Exact Mass	992.640015
PSA	174.66000
LogP	9.18
Vapour Pressure	0.0±0.6 mmHg at 25°C
Index of Refraction	1.499

Hazard Codes	Xi

2',4''-O-bis(tr...

CAS#:119665-78-0

methyl iodide

CAS#:74-88-4

~99%

6-O-Methyl-2',4...

CAS#:119665-62-2

Literature: US2010/280230 A1, ; Page/Page column 3 ;

Precursor 1
CAS#:74-88-4 methyl iodide
DownStream 1
CAS#:114-07-8 Erythromycin

(3R,4S,5S,6R,7R,9R,10E,11S,12R,13S,14R)-6-({(2S,3R,4S,6R)-4-(Dimethylamino)-6-methyl-3-[(trimethylsilyl)oxy]tetrahydro-2H-pyran-2-yl}oxy)-10-{[(2-ethoxy-2-propanyl)oxy]imino}-14-ethyl-12,13-dihydroxy-7-methoxy-4-({(2R,4R,5S,6S)-4-methoxy-4,6-dimethyl-5-[(trimethylsilyl)oxy]tetrahydro-2H-pyran-2-yl}oxy)-3,5,7,9,11,13-hexamethyloxacyclotetradecan-2-one

6-O-Methyl-2',4''-bis-O-(trimethylsilyl)-9-[O-(1-ethoxy-1-methylethyl)oxime]-Erythromycin