N-Benzyl-N-bis(PEG1-OH)

Modify Date: 2024-01-16 20:34:22

N-Benzyl-N-bis(PEG1-OH) Structure
N-Benzyl-N-bis(PEG1-OH) structure
Common Name N-Benzyl-N-bis(PEG1-OH)
CAS Number 119580-47-1 Molecular Weight 283.36
Density N/A Boiling Point N/A
Molecular Formula C15H25NO4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of N-Benzyl-N-bis(PEG1-OH)


N-Benzyl-N-bis-PEG2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name N-Benzyl-N-bis-PEG2
Synonym More Synonyms

 N-Benzyl-N-bis(PEG1-OH) Biological Activity

Description N-Benzyl-N-bis-PEG2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C15H25NO4
Molecular Weight 283.36

 Synonyms

MFCD00429254