AZD 8683
Modify Date: 2025-09-18 15:32:26
AZD 8683 structure
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Common Name | AZD 8683 | ||
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| CAS Number | 1194737-07-9 | Molecular Weight | 542.518 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C28H36BrN3O3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of AZD 8683A highly potent, long acting muscarinic receptor M3 antagonist with pIC50 of 9.8, inhibits M3 receptor in guinea pig trachea with pA2 of 9.4; reverse airflow obstruction by antagonizing para-sympathetic bronchoconstricting effects within the airways, shows potential for chronic obstructive pulmonary disease (COPD) management. COPD Phase 2 Discontinued |
| Name | AZD 8683 |
|---|
| Description | A highly potent, long acting muscarinic receptor M3 antagonist with pIC50 of 9.8, inhibits M3 receptor in guinea pig trachea with pA2 of 9.4; reverse airflow obstruction by antagonizing para-sympathetic bronchoconstricting effects within the airways, shows potential for chronic obstructive pulmonary disease (COPD) management. COPD Phase 2 Discontinued |
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| References | References 1. Mete A, et al. Bioorg Med Chem Lett. 2013 Dec 1;23(23):6248-53. 2. Mastrodicasa MA, et al. Expert Opin Investig Drugs. 2017 Feb;26(2):161-174. View Related Products by Target mAChR COPD |
| Molecular Formula | C28H36BrN3O3 |
|---|---|
| Molecular Weight | 542.518 |