HTS07545

Modify Date: 2024-01-06 19:06:17

HTS07545 Structure
HTS07545 structure
Common Name HTS07545
CAS Number 118666-03-8 Molecular Weight 358.39
Density N/A Boiling Point N/A
Molecular Formula C22H18N2O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of HTS07545


HTS07545 is a potent sulfide:quinone oxidoreductase (SQOR) inhibitor with an IC50 of 30 nM. HTS07545 decrease the rate of breakdown of hydrogen sulfide (H2S). HTS07545 can be used for heart failure research[1].

 Names

Name HTS07545

 HTS07545 Biological Activity

Description HTS07545 is a potent sulfide:quinone oxidoreductase (SQOR) inhibitor with an IC50 of 30 nM. HTS07545 decrease the rate of breakdown of hydrogen sulfide (H2S). HTS07545 can be used for heart failure research[1].
Related Catalog
Target

IC50: 30 nM (SQOR)[1]

References

[1]. Simon D P Baugh, et al. Synthesis and evaluation of potent novel inhibitors of human sulfide:quinone oxidoreductase. Bioorg Med Chem Lett. 2021 Dec 15;54:128443.

 Chemical & Physical Properties

Molecular Formula C22H18N2O3
Molecular Weight 358.39