DSP-6952 hydrobromide
Modify Date: 2025-09-19 11:10:16
DSP-6952 hydrobromide structure
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Common Name | DSP-6952 hydrobromide | ||
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| CAS Number | 1184661-33-3 | Molecular Weight | 535.864 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C21H32BrClN4O5 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of DSP-6952 hydrobromideDSP-6952 is a novel potent, selective, orally active 5-HT4 receptor partial agonist with Ki of 50-100 nM for human 5-HT4a/4b/4c; enhances gastric motility and causes colonic giant migrating contractions (GMCs) associated with defecation in conscious dogs, having ED50 value for inducing GMCs of 1.56 mg/kg; rapidly increases fecal wet weight without increasing fluid content in mice (1-10 mg/kg, p.o.). |
| Name | DSP-6952 hydrobromide |
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| Description | DSP-6952 is a novel potent, selective, orally active 5-HT4 receptor partial agonist with Ki of 50-100 nM for human 5-HT4a/4b/4c; enhances gastric motility and causes colonic giant migrating contractions (GMCs) associated with defecation in conscious dogs, having ED50 value for inducing GMCs of 1.56 mg/kg; rapidly increases fecal wet weight without increasing fluid content in mice (1-10 mg/kg, p.o.). |
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| References | References 1. Mine Y, et al. Eur J Pharmacol. 2018 Feb 9;826:123-132. 2. Tsubouchi T, et al. Eur J Pharmacol. 2018 Mar 1;826:96-105. View Related Products by Target 5-HT Receptor |
| Molecular Formula | C21H32BrClN4O5 |
|---|---|
| Molecular Weight | 535.864 |
| InChIKey | PYPGYTWIVPXWHE-RSAXXLAASA-N |
| SMILES | Br.COc1cc(N)c(Cl)cc1C(=O)NCC1CN(CC2CCN(C(=O)CO)CC2)CCO1 |