40616-75-9

40616-75-9 structure

Name: DSP-4
Chemical Name: N-(2-Chloroethyl)-N-ethyl-2-bromobenzylamine hydrochloride
CAS Number: 40616-75-9
Molecular Formula: C₁₁H₁₆BrCl₂N
Molecular Weight: 313.06100
Catalog: Research Areas Neurological Disease
Create Date: 2019-02-16 13:15:06
Modify Date: 2024-01-03 18:06:40
DSP-4 hydrochloride (Neurotoxin DSP 4 hydrochloride) is a highly selective neurotoxin and readily passes the blood-brain barrier with neurotoxic effects on noradrenergic neurons of adult and developing rats, can be used for the temporary selective degradation of the central and peripheral noradrenergic neurons, mainly those from the locus coeruleus (LC)[1][2].

Name	N-(2-Chloroethyl)-N-ethyl-2-bromobenzylamine hydrochloride
Synonyms	MFCD00043241 N-[(2-bromophenyl)methyl]-2-chloro-N-ethylethanamine,hydrochloride DSP-4 N-Ethyl-N-(2-chloroethyl)-2-bromobenzylamine hydrochloride

Description	DSP-4 hydrochloride (Neurotoxin DSP 4 hydrochloride) is a highly selective neurotoxin and readily passes the blood-brain barrier with neurotoxic effects on noradrenergic neurons of adult and developing rats, can be used for the temporary selective degradation of the central and peripheral noradrenergic neurons, mainly those from the locus coeruleus (LC)[1][2].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Neurological Disease
References	[1]. Hormigo S, et al. The selective neurotoxin DSP-4 impairs the noradrenergic projections from the locus coeruleus to the inferior colliculus in rats. Front Neural Circuits. 2012 Jun 28;6:41. [2]. Jaim-Etcheverry G, et al. DSP-4: a novel compound with neurotoxic effects on noradrenergic neurons of adult and developing rats. Brain Res. 1980 Apr 28;188(2):513-23.

CHEMICAL NAME :: Benzylamine, o-bromo-N-(2-chloroethyl)-N-ethyl-, hydrochloride

REFERENCE :: APSXAS Acta Pharmaceutica Suecica. (Apotekarsocieteten-Farmacevtiska Foereningen, Box 1136, S-111, 81 Stockholm, Sweden) V.1- 1964- Volume(issue)/page/year: 10,29,1973

REFERENCE :: APSXAS Acta Pharmaceutica Suecica. (Apotekarsocieteten-Farmacevtiska Foereningen, Box 1136, S-111, 81 Stockholm, Sweden) V.1- 1964- Volume(issue)/page/year: 10,29,1973

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	DP1726100
HS Code	2921499090

HS Code	2921499090
Summary	2921499090 other aromatic monoamines and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%