Methyl 3,4,5-trimethoxybenzoate-d9

Modify Date: 2025-08-25 18:15:25

Methyl 3,4,5-trimethoxybenzoate-d9 Structure
Methyl 3,4,5-trimethoxybenzoate-d9 structure
Common Name Methyl 3,4,5-trimethoxybenzoate-d9
CAS Number 1182838-07-8 Molecular Weight 235.281
Density 1.1±0.1 g/cm3 Boiling Point 274.5±0.0 °C at 760 mmHg
Molecular Formula C11H5D9O5 Melting Point N/A
MSDS N/A Flash Point 115.2±18.2 °C

 Use of Methyl 3,4,5-trimethoxybenzoate-d9


Methyl 3,4,5-trimethoxybenzoate-d9 is the deuterium labeled Methyl 3,4,5-trimethoxybenzoate[1]. Methyl 3,4,5-trimethoxybenzoate can be synthesized from Gallic acid. Methyl 3,4,5-trimethoxybenzoate is mainly used in the production of Trimethoprim (TMP), Sulfa synergistic intermediates, and many other agents[2].

 Names

Name Methyl 3,4,5-tris[(2H3)methyloxy]benzoate
Synonym More Synonyms

 Methyl 3,4,5-trimethoxybenzoate-d9 Biological Activity

Description Methyl 3,4,5-trimethoxybenzoate-d9 is the deuterium labeled Methyl 3,4,5-trimethoxybenzoate[1]. Methyl 3,4,5-trimethoxybenzoate can be synthesized from Gallic acid. Methyl 3,4,5-trimethoxybenzoate is mainly used in the production of Trimethoprim (TMP), Sulfa synergistic intermediates, and many other agents[2].
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

[2]. Method for synthesizing methyl 3,4,5-trimethoxybenzoate from gallic acid. CN105732375A.

 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Boiling Point 274.5±0.0 °C at 760 mmHg
Molecular Formula C11H5D9O5
Molecular Weight 235.281
Flash Point 115.2±18.2 °C
Exact Mass 235.140610
LogP 1.74
Vapour Pressure 0.0±0.5 mmHg at 25°C
Index of Refraction 1.494

 Synonyms

Benzoic acid, 3,4,5-tris(methyl-d3-oxy)-, methyl ester
Methyl 3,4,5-tris[(2H3)methyloxy]benzoate
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