Acetylepipodophyllotoxin

Modify Date: 2024-01-01 22:24:23

Acetylepipodophyllotoxin Structure
Acetylepipodophyllotoxin structure
Common Name Acetylepipodophyllotoxin
CAS Number 1180-35-4 Molecular Weight 456.44
Density 1.4±0.1 g/cm3 Boiling Point 595.3±50.0 °C at 760 mmHg
Molecular Formula C24H24O9 Melting Point N/A
MSDS N/A Flash Point 257.3±30.2 °C

 Use of Acetylepipodophyllotoxin


Epipodophyllotoxin acetate (4-O-Epipodophyllotoxinyl acetate; compound 4) is a cyclolignan that exhibits antineoplastic and antiviral activities. Epipodophyllotoxin acetate inhibits HSV and VSV, with IC50s of 0.2 and 0.1 μg/mL, respectively[1].

 Names

Name (5S,5aR,8aR,9R)-8-Oxo-9-(3,4,5-trimethoxyphenyl)-5,5a,6,8,8a,9-he xahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol-5-yl acetate
Synonym More Synonyms

 Acetylepipodophyllotoxin Biological Activity

Description Epipodophyllotoxin acetate (4-O-Epipodophyllotoxinyl acetate; compound 4) is a cyclolignan that exhibits antineoplastic and antiviral activities. Epipodophyllotoxin acetate inhibits HSV and VSV, with IC50s of 0.2 and 0.1 μg/mL, respectively[1].
Related Catalog
References

[1]. Feliciano AS, et, al. Antineoplastic and antiviral activities of some cyclolignans. Planta Med. 1993 Jun;59(3):246-9.  

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 595.3±50.0 °C at 760 mmHg
Molecular Formula C24H24O9
Molecular Weight 456.44
Flash Point 257.3±30.2 °C
Exact Mass 456.142029
PSA 98.75000
LogP 2.03
Vapour Pressure 0.0±1.7 mmHg at 25°C
Index of Refraction 1.613

 Safety Information

Hazard Codes Xi

 Precursor & DownStream

Precursor  2

DownStream  0

 Synonyms

ethynyl-magnesium bromide
Ethynylmagnesium bromide solution
O-Acetyl-epipodophyllotoxin
Furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one, 9-(acetyloxy)-5,8,8a,9-tetrahydro-5-(3,4,5-trimethoxyphenyl)-, (5R,5aR,8aR,9S)-
acetylepipodophyllotoxin
ethynyl-MgBr
(5S,5aR,8aR,9R)-8-Oxo-9-(3,4,5-trimethoxyphenyl)-5,5a,6,8,8a,9-hexahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol-5-yl acetate
acetylenemagnesium bromide
acetylenyl magnesium bromide
bromomagnesium acetylide
epipodophyllotoxin acetate
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