VA-K-14 hydrochloride

Modify Date: 2025-09-05 18:17:52

VA-K-14 hydrochloride Structure
VA-K-14 hydrochloride structure
Common Name VA-K-14 hydrochloride
CAS Number 1171341-19-7 Molecular Weight 305.397
Density 1.3±0.1 g/cm3 Boiling Point 510.1±52.0 °C at 760 mmHg
Molecular Formula C18H16ClN3S Melting Point N/A
MSDS N/A Flash Point 262.3±30.7 °C

 Use of VA-K-14 hydrochloride


VA-K-14 hydrochloride is a specific thyroid-stimulating hormone receptor (TSHR) antagonist (IC50= 12.3 μM)[1].

 Names

Name N-Methyl-4-(2-phenyl-1H-indol-3-yl)-1,3-thiazol-2-amine
Synonym More Synonyms

 VA-K-14 hydrochloride Biological Activity

Description VA-K-14 hydrochloride is a specific thyroid-stimulating hormone receptor (TSHR) antagonist (IC50= 12.3 μM)[1].
Related Catalog
References

[1]. Latif R, et al. TSH Receptor Signaling Abrogation by a Novel Small Molecule. Front Endocrinol (Lausanne). 2016;7:130. Published 2016 Sep 27.

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 510.1±52.0 °C at 760 mmHg
Molecular Formula C18H16ClN3S
Molecular Weight 305.397
Flash Point 262.3±30.7 °C
Exact Mass 305.098663
LogP 4.33
Vapour Pressure 0.0±1.3 mmHg at 25°C
Index of Refraction 1.732

 Synonyms

MFCD10180795
2-Thiazolamine, N-methyl-4-(2-phenyl-1H-indol-3-yl)-
N-Methyl-4-(2-phenyl-1H-indol-3-yl)-1,3-thiazol-2-amine
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