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1171341-19-7

1171341-19-7 structure
1171341-19-7 structure
  • Name: VA-K-14 hydrochloride
  • Chemical Name: N-Methyl-4-(2-phenyl-1H-indol-3-yl)-1,3-thiazol-2-amine
  • CAS Number: 1171341-19-7
  • Molecular Formula: C18H16ClN3S
  • Molecular Weight: 305.397
  • Catalog: Signaling Pathways GPCR/G Protein TSH Receptor
  • Create Date: 2021-09-13 10:54:32
  • Modify Date: 2024-01-09 20:02:20
  • VA-K-14 hydrochloride is a specific thyroid-stimulating hormone receptor (TSHR) antagonist (IC50= 12.3 μM)[1].

Name N-Methyl-4-(2-phenyl-1H-indol-3-yl)-1,3-thiazol-2-amine
Synonyms MFCD10180795
2-Thiazolamine, N-methyl-4-(2-phenyl-1H-indol-3-yl)-
N-Methyl-4-(2-phenyl-1H-indol-3-yl)-1,3-thiazol-2-amine
Description VA-K-14 hydrochloride is a specific thyroid-stimulating hormone receptor (TSHR) antagonist (IC50= 12.3 μM)[1].
Related Catalog
References

[1]. Latif R, et al. TSH Receptor Signaling Abrogation by a Novel Small Molecule. Front Endocrinol (Lausanne). 2016;7:130. Published 2016 Sep 27.

Density 1.3±0.1 g/cm3
Boiling Point 510.1±52.0 °C at 760 mmHg
Molecular Formula C18H16ClN3S
Molecular Weight 305.397
Flash Point 262.3±30.7 °C
Exact Mass 305.098663
LogP 4.33
Vapour Pressure 0.0±1.3 mmHg at 25°C
Index of Refraction 1.732