Tulopafant
Modify Date: 2024-01-05 14:26:59
Tulopafant structure
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Common Name | Tulopafant | ||
|---|---|---|---|---|
| CAS Number | 116289-53-3 | Molecular Weight | 425.50200 | |
| Density | 1.32g/cm3 | Boiling Point | 613.3ºC at 760mmHg | |
| Molecular Formula | C25H19N3O2S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 324.7ºC | |
Use of TulopafantTulopafant is a platelet activating factor (PAF) antagonist. |
| Name | N-(3-benzoylphenyl)-3-pyridin-3-yl-1,3-dihydropyrrolo[1,2-c][1,3]thiazole-7-carboxamide |
|---|---|
| Synonym | More Synonyms |
| Description | Tulopafant is a platelet activating factor (PAF) antagonist. |
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| Related Catalog | |
| In Vitro | Preincubation of neutrophils with Tulopafant (RP 59227) results in a concentration-dependent decrease in chemiluminescence produced by PAF primed cells[1]. |
| In Vivo | Tulopafant (RP 59227) effectively reduces myocardial infarct size and reduces the incidence of ischemia and reperfusion-induced arrhythmias in barbital-anesthetized dogs[1].Histological examination reveals marked diminution of both interstitial hemorrhage and deposition of platelet and granulocytes in capillaries of cardiac xenografts when recipient animals are pretreated with Tulopafant[2]. |
| References |
| Density | 1.32g/cm3 |
|---|---|
| Boiling Point | 613.3ºC at 760mmHg |
| Molecular Formula | C25H19N3O2S |
| Molecular Weight | 425.50200 |
| Flash Point | 324.7ºC |
| Exact Mass | 425.12000 |
| PSA | 89.29000 |
| LogP | 5.23310 |
| Vapour Pressure | 5.63E-15mmHg at 25°C |
| Index of Refraction | 1.702 |
| Storage condition | 2-8℃ |
| Tulopafant |
| Tulopafantum |
| UNII-IQ3Q8N1287 |