SB-206606

Modify Date: 2024-01-09 19:26:51

SB-206606 Structure
SB-206606 structure
Common Name SB-206606
CAS Number 116049-78-6 Molecular Weight 363.84
Density N/A Boiling Point N/A
Molecular Formula C19H22ClNO4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of SB-206606


SB-206606, a stereoisomer of BRL 37344, is a potentially specific, beta 3-adrenergic receptor (β3-AR) ligand. The affinity of [3H]SB 206606 is 76 times higher for the β3-AR than for the beta 1/beta 2-adrenergic receptors[1].

 Names

Name SB-206606

 SB-206606 Biological Activity

Description SB-206606, a stereoisomer of BRL 37344, is a potentially specific, beta 3-adrenergic receptor (β3-AR) ligand. The affinity of [3H]SB 206606 is 76 times higher for the β3-AR than for the beta 1/beta 2-adrenergic receptors[1].
Related Catalog
Target

Beta-3 adrenergic receptor

In Vitro [3H]SB-206606 binding to membranes from Chinese hamster ovary K1 cells transfected with the rat β3-AR with a Kd value of 58 nM[1]. [3H]SB-206606 binding to brown adipose tissue where beta 1-, beta 2-, and beta 3-adrenergic receptor subtypes are known to coexist with a Kd value of 38 nM[1].
References

[1]. Muzzin P, et al. Characterization of a new, highly specific, beta 3-adrenergic receptor radioligand, [3H]SB 206606. Mol Pharmacol. 1994 Aug;46(2):357-63. PMID: 8078497.

 Chemical & Physical Properties

Molecular Formula C19H22ClNO4
Molecular Weight 363.84
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