FD-1080 free acid

Modify Date: 2023-02-16 18:01:49

FD-1080 free acid structure	Common Name	FD-1080 free acid
	CAS Number	1151888-25-3	Molecular Weight	743.33
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₄₀H₃₉ClN₂O₆S₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of FD-1080 free acid

FD-1080 free acid is a fluorophore with both excitation and emission in the NIR-II region (Ex=1064 nm, Em=1080 nm). FD-1080 free acid can be used for in vivo imaging[1].

Name	FD-1080 free acid

Description	FD-1080 free acid is a fluorophore with both excitation and emission in the NIR-II region (Ex=1064 nm, Em=1080 nm). FD-1080 free acid can be used for in vivo imaging[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
In Vitro	FD-1080 shows superior photostability under the continuous laser irradiation. The quantum yield of FD-1080 is 0.31%, and can be increased to 5.94% after combining with fetal bovine serum (FBS) to form FD-1080-FBS complexes[1].
In Vivo	The 1064 nm NIR-II excitation of FD-1080 is demonstrated with the high tissue penetration depth and superior imaging resolution compared to NIR excitation from 650 nm to 980 nm. Deeptissue and high-resolution in vivo imaging for the left hindlimb vasculature, abdomen, and brain vessels was realized, allowing penetration through intact skin, tissue, and skull. FD-1080 also quantifying the respiratory rate based on the dynamic imaging of respiratory craniocaudal motion of the liver for the awake and anaesthetized mouse[1].
References	[1]. Benhao Li, et al. An Efficient 1064 nm NIR-II Excitation Fluorescent Molecular Dye for Deep-Tissue High-Resolution Dynamic Bioimaging. Angew Chem Int Ed Engl. 2018 Jun 18;57(25):7483-7487.

Molecular Formula	C₄₀H₃₉ClN₂O₆S₂
Molecular Weight	743.33