trans-1-tert-Butyl 2-methyl 4-hydroxypyrrolidine-1,2-dicarboxylate

Modify Date: 2024-04-03 10:51:26

trans-1-tert-Butyl 2-methyl 4-hydroxypyrrolidine-1,2-dicarboxylate structure	Common Name	trans-1-tert-Butyl 2-methyl 4-hydroxypyrrolidine-1,2-dicarboxylate
	CAS Number	1145663-09-7	Molecular Weight	245.27
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₁H₁₉NO₅	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of trans-1-tert-Butyl 2-methyl 4-hydroxypyrrolidine-1,2-dicarboxylate

rel-Boc-Hyp-OMe is the inactive isomer of Boc-Hyp-OMe (HY-65039), and can be used as an experimental control. Boc-Hyp-OMe is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Boc-Hyp-OMe is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1][2].

Name	rel-Boc-Hyp-OMe

Description	rel-Boc-Hyp-OMe is the inactive isomer of Boc-Hyp-OMe (HY-65039), and can be used as an experimental control. Boc-Hyp-OMe is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Boc-Hyp-OMe is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1][2].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
References	[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017;16(5):315-337. [2]. Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985.

Description

Related Catalog

Research Areas >> Cancer

Signaling Pathways >> Others >> Others

References

[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017;16(5):315-337.

[2]. Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985.