POP-3MB

Modify Date: 2025-09-24 11:31:01

POP-3MB structure	Common Name	POP-3MB
	CAS Number	1144114-27-1	Molecular Weight	605.79
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₃₈H₃₉NO₄S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of POP-3MB

POP-3MB (compound 1b) is an ICMT inhibitor (IC50: 2.5 μM). POP-3MB changes the subcellular localization of K-Ras and inhibits Ras activation. POP-3MB also inhibits Erk phosphorylation[1].

Name	POP-3MB

Description	POP-3MB (compound 1b) is an ICMT inhibitor (IC50: 2.5 μM). POP-3MB changes the subcellular localization of K-Ras and inhibits Ras activation. POP-3MB also inhibits Erk phosphorylation[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> MAPK/ERK Pathway >> ERK Signaling Pathways >> Stem Cell/Wnt >> ERK
Target	IC50: 2.5 μM (ICMT)[1]
References	[1]. Majmudar JD et al. Amide-modified prenylcysteine based Icmt inhibitors: Structure-activity relationships, kinetic analysis and cellular characterization. Bioorg Med Chem. 2012 Jan 1;20(1):283-95.

Molecular Formula	C₃₈H₃₉NO₄S
Molecular Weight	605.79

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