2,3-Dehydro-3,4-dihydro ivermectin

Modify Date: 2025-08-20 09:14:55

2,3-Dehydro-3,4-dihydro ivermectin Structure
2,3-Dehydro-3,4-dihydro ivermectin structure
 Common Name 2,3-Dehydro-3,4-dihydro ivermectin
CAS Number 1135339-49-9 Molecular Weight 875.09300
Density N/A Boiling Point N/A
Molecular Formula C48H74O14 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 2,3-Dehydro-3,4-dihydro ivermectin


2,3-Dehydro-3,4-dihydro ivermectin is an analog of ivermectin (HY-15310) and an anthelmintic. 2,3-Dehydro-3,4-dihydro ivermectin has activity against L. amazonensis promastigotes and amastigotes (IC50s=13.8 and 3.6 µM, respectively) without inducing cytotoxicity to macrophages (IC50= 65.5 µM).

 Names

Name Avermectin A1a, 2,​3-​didehydro-​5-​O-​demethyl-​3,​4,​22,​23-​tetrahydro-​, (4S)​

 2,3-Dehydro-3,4-dihydro ivermectin Biological Activity

Description 2,3-Dehydro-3,4-dihydro ivermectin is an analog of ivermectin (HY-15310) and an anthelmintic. 2,3-Dehydro-3,4-dihydro ivermectin has activity against L. amazonensis promastigotes and amastigotes (IC50s=13.8 and 3.6 µM, respectively) without inducing cytotoxicity to macrophages (IC50= 65.5 µM).

 Chemical & Physical Properties

Molecular Formula C48H74O14
Molecular Weight 875.09300
Exact Mass 874.50800
PSA 170.06000
LogP 5.60140
InChIKey AZSRBVAPBFWEGT-GWDABAGCSA-N
SMILES CCC(C)C1OC2(CCC1C)CC1CC(CC=C(C)C(OC3CC(OC)C(OC4CC(OC)C(O)C(C)O4)C(C)O3)C(C)C=CC=C3COC4C(O)C(C)C=C(C(=O)O1)C34O)O2
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Chemsrc provides 2,3-Dehydro-3,4-dihydro ivermectin(CAS#:1135339-49-9) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of 2,3-Dehydro-3,4-dihydro ivermectin are included as well.>> amp version: 2,3-Dehydro-3,4-dihydro ivermectin

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