2,3-Dehydro-3,4-dihydro ivermectin
Names
[ CAS No. ]:
1135339-49-9
[ Name ]:
2,3-Dehydro-3,4-dihydro ivermectin
Biological Activity
[Description]:
2,3-Dehydro-3,4-dihydro ivermectin is an analog of ivermectin (HY-15310) and an anthelmintic. 2,3-Dehydro-3,4-dihydro ivermectin has activity against L. amazonensis promastigotes and amastigotes (IC50s=13.8 and 3.6 µM, respectively) without inducing cytotoxicity to macrophages (IC50= 65.5 µM).
Chemical & Physical Properties
[ Molecular Formula ]:
C48H74O14
[ Molecular Weight ]:
875.09300
[ Exact Mass ]:
874.50800
[ PSA ]:
170.06000
[ LogP ]:
5.60140