Quizartinib hydrochloride

Modify Date: 2024-02-05 21:05:28

Quizartinib hydrochloride Structure
Quizartinib hydrochloride structure
Common Name Quizartinib hydrochloride
CAS Number 1132827-21-4 Molecular Weight 633.58900
Density N/A Boiling Point N/A
Molecular Formula C29H34Cl2N6O4S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Quizartinib hydrochloride


Quizartinib (AC220) is a potent, selective, second-generation FLT3 inhibitor with Kd of 1.6 nM, inhibits Wt FLT3 and FLT3-ITD autophosphorylation in MV4-11cell with IC50 of 4.2 and 1.1 nM, respectively.

 Names

Name 1-(5-tert-butyl-1,2-oxazol-3-yl)-3-[4-[6-(2-morpholin-4-ylethoxy)imidazo[2,1-b][1,3]benzothiazol-2-yl]phenyl]urea,dihydrochloride
Synonym More Synonyms

 Chemical & Physical Properties

Molecular Formula C29H34Cl2N6O4S
Molecular Weight 633.58900
Exact Mass 632.17400
PSA 137.63000
LogP 6.89330

 Synonyms

UNII-WK7Q6ZIZ10
Quizartinib dihydrochloride
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