1132827-21-4
1132827-21-4 structure
- Name: Quizartinib hydrochloride
- Chemical Name: 1-(5-tert-butyl-1,2-oxazol-3-yl)-3-[4-[6-(2-morpholin-4-ylethoxy)imidazo[2,1-b][1,3]benzothiazol-2-yl]phenyl]urea,dihydrochloride
- CAS Number: 1132827-21-4
- Molecular Formula: C29H34Cl2N6O4S
- Molecular Weight: 633.58900
- Create Date: 2016-08-21 15:06:11
- Modify Date: 2024-02-05 21:05:28
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Quizartinib (AC220) is a potent, selective, second-generation FLT3 inhibitor with Kd of 1.6 nM, inhibits Wt FLT3 and FLT3-ITD autophosphorylation in MV4-11cell with IC50 of 4.2 and 1.1 nM, respectively.
| Name | 1-(5-tert-butyl-1,2-oxazol-3-yl)-3-[4-[6-(2-morpholin-4-ylethoxy)imidazo[2,1-b][1,3]benzothiazol-2-yl]phenyl]urea,dihydrochloride |
|---|---|
| Synonyms |
UNII-WK7Q6ZIZ10
Quizartinib dihydrochloride |
| Molecular Formula | C29H34Cl2N6O4S |
|---|---|
| Molecular Weight | 633.58900 |
| Exact Mass | 632.17400 |
| PSA | 137.63000 |
| LogP | 6.89330 |