L-Ascorbic acid 2-phosphate magnesium
Modify Date: 2025-08-22 19:56:52
L-Ascorbic acid 2-phosphate magnesium structure
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Common Name | L-Ascorbic acid 2-phosphate magnesium | ||
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| CAS Number | 113170-55-1 | Molecular Weight | 278.393 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C6H9O9P.3/2Mg | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of L-Ascorbic acid 2-phosphate magnesiumL-Ascorbic acid 2-phosphate magnesium (2-Phospho-L-ascorbic acid magnesium) is a long-acting vitamin C derivative that can stimulate collagen formation and expression[1]. L-Ascorbic acid 2-phosphate magnesium (2-Phospho-L-ascorbic acid magnesium) can be used as a culture medium supplement for the osteogenic differentiation of human adipose stem cells (hASCs). L-Ascorbic acid 2-phosphate magnesium (2-Phospho-L-ascorbic acid magnesium) increases alkaline phosphatase (ALP) activity and expression of runx2A in hASCs during the osteogenic differentiation[2][3]. |
| Name | L-Ascorbic acid 2-phosphate sesquimagnesium salt hydrate |
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| Synonym | More Synonyms |
| Description | L-Ascorbic acid 2-phosphate magnesium (2-Phospho-L-ascorbic acid magnesium) is a long-acting vitamin C derivative that can stimulate collagen formation and expression[1]. L-Ascorbic acid 2-phosphate magnesium (2-Phospho-L-ascorbic acid magnesium) can be used as a culture medium supplement for the osteogenic differentiation of human adipose stem cells (hASCs). L-Ascorbic acid 2-phosphate magnesium (2-Phospho-L-ascorbic acid magnesium) increases alkaline phosphatase (ALP) activity and expression of runx2A in hASCs during the osteogenic differentiation[2][3]. |
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| Related Catalog | |
| Target |
IC50: alkaline phosphatase (ALP); collagen formation; runx2A[2][3] |
| In Vitro | L-Ascorbic acid 2-phosphate (0.1-1.5 mM; 2 to 3 weeks with medium exchange every 2 to 3 days) significantly stimulates cell growth, whereas addition of l-Ascorbic acid (Asc) achieves only weak growth stimulation. A combination of Asc-2P and bFGF significantly increases cell growth, but supplementation with EGF and/or insulin does not have any additional effect [1]. L-Ascorbic acid 2-phosphate (50 µM-250 µM) is needed for the effective osteogenic differentiation of human adipose stem cells (hASCs), and higher concentrations of AsA2-P results in increased runx2 expression and ALP activity. The highest proliferation, ALP activity and runx2 expression is achieved with 150 µM AsA2-P and 10 nM dexamethasone (Dex), and 250 µM AsA2-P and 5 nM Dex[3]. Cell Viability Assay[1] Cell Line: Human corneal endothelial cells (HCECs) Concentration: 0.1 mM; 0.3 mM; 1.5 mM Incubation Time: 2 to 3 weeks with medium exchange every 2 to 3 days Result: Stimulated HCEC cells growth. |
| References |
| Molecular Formula | C6H9O9P.3/2Mg |
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| Molecular Weight | 278.393 |
| Exact Mass | 277.967804 |
| PSA | 169.22000 |
| Hazard Codes | Xi |
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| Risk Phrases | 36/37/38 |
| Safety Phrases | 26-36/37/39 |
| HS Code | 2835100000 |
| HS Code | 2835100000 |
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| trimagnesium,[(2R)-2-[(1S)-1,2-dihydroxyethyl]-3-oxido-5-oxo-2H-furan-4-yl] phosphate |
| L-Ascorbic Acid 2-Phosphate Sesquimagnesium Salt Hydrate |
| Magnesium (5R)-5-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-2-oxo-2,5-dihydro-3-furanyl phosphate |
| MFCD08063372 |