NSC 228155
Modify Date: 2024-01-08 21:43:16
NSC 228155 structure
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Common Name | NSC 228155 | ||
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| CAS Number | 113104-25-9 | Molecular Weight | 290.255 | |
| Density | 1.7±0.1 g/cm3 | Boiling Point | 627.3±65.0 °C at 760 mmHg | |
| Molecular Formula | C11H6N4O4S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 333.2±34.3 °C | |
Use of NSC 228155NSC 228155 is a potent inhibitor of KIX-KID interaction, inhibits kinase-inducible domain (KID) from CREB and KID-interacting domain (KIX) from CBP, with an IC50 of 0.36 μM. NSC 228155 is not selective against CREB-mediated gene transcription in living HEK 293T cells[1]. |
| Name | 4-Nitro-7-[(1-oxido-2-pyridinyl)sulfanyl]-2,1,3-benzoxadiazole |
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| Synonym | More Synonyms |
| Description | NSC 228155 is a potent inhibitor of KIX-KID interaction, inhibits kinase-inducible domain (KID) from CREB and KID-interacting domain (KIX) from CBP, with an IC50 of 0.36 μM. NSC 228155 is not selective against CREB-mediated gene transcription in living HEK 293T cells[1]. |
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| Related Catalog | |
| Target |
IC50: 0.36 μM (KIX-KID)[1] |
| In Vitro | NSC 228155 (Compound 1) inhibits CREB- and VP16-CREB-mediated gene transcription in living HEK 293T cells with an IC50 of 2.09 and 6.14 μM, respectively[1]. |
| References |
| Density | 1.7±0.1 g/cm3 |
|---|---|
| Boiling Point | 627.3±65.0 °C at 760 mmHg |
| Molecular Formula | C11H6N4O4S |
| Molecular Weight | 290.255 |
| Flash Point | 333.2±34.3 °C |
| Exact Mass | 290.010986 |
| LogP | 0.07 |
| Vapour Pressure | 0.0±1.8 mmHg at 25°C |
| Index of Refraction | 1.793 |
| Storage condition | -20℃ |
| 4-Nitro-7-[(1-oxido-2-pyridinyl)sulfanyl]-2,1,3-benzoxadiazole |
| 2,1,3-Benzoxadiazole, 4-nitro-7-[(1-oxido-2-pyridinyl)thio]- |