Benzquinamide hydrochloride
Modify Date: 2025-08-27 14:26:24
Benzquinamide hydrochloride structure
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Common Name | Benzquinamide hydrochloride | ||
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| CAS Number | 113-69-9 | Molecular Weight | 440.96 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C22H33ClN2O5 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Benzquinamide hydrochlorideBenzquinamide (P2647) is an antiemetic which can bind to the α2A, α2B, and α2C adrenergic receptors (α2-AR) with Ki values of 1,365, 691, and 545 nM, respectively. Benzquinamide also inhibits P-glycoprotein mediated drug efflux and potentiates anticancer agent cytotoxicity in multidrug resistant cells[1][2]. |
| Name | 3-carbamoyl-N,N-diethyl-1,3,4,6,7,11b-hexahydro-9,11-dimethoxy-2H-benzo[a]quinolizin-2-yl acetate hydrochloride |
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| Synonym | More Synonyms |
| Description | Benzquinamide (P2647) is an antiemetic which can bind to the α2A, α2B, and α2C adrenergic receptors (α2-AR) with Ki values of 1,365, 691, and 545 nM, respectively. Benzquinamide also inhibits P-glycoprotein mediated drug efflux and potentiates anticancer agent cytotoxicity in multidrug resistant cells[1][2]. |
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| Related Catalog | |
| Target |
Ki: 1,365, 691, and 545 nM (α2A, α2B,α2C receptor)[1] |
| References |
| Molecular Formula | C22H33ClN2O5 |
|---|---|
| Molecular Weight | 440.96 |
| InChIKey | KZLNXGBVFTWMPS-UHFFFAOYSA-N |
| SMILES | CCN(CC)C(=O)C1CN2CCc3cc(OC)c(OC)cc3C2CC1OC(C)=O.Cl |
| EINECS 204-033-3 |