Aztreonam-d6
Modify Date: 2024-01-08 11:55:45
Aztreonam-d6 structure
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Common Name | Aztreonam-d6 | ||
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| CAS Number | 1127452-94-1 | Molecular Weight | 441.47 | |
| Density | 1.8±0.1 g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C13H11D6N5O8S2 | Melting Point | >210°C | |
| MSDS | N/A | Flash Point | N/A | |
Use of Aztreonam-d6Aztreonam-d6 is deuterium labeled Aztreonam. Aztreonam (SQ-26,776) is a synthetic monocyclic beta-lactam antibiotic, which has a very high affinity for penicillin-binding protein 3 (PBP-3). |
| Name | 2-({(Z)-[1-(2-Amino-1,3-thiazol-4-yl)-2-{[(2S,3S)-2-methyl-4-oxo-1-sulfo-3-azetidinyl]amino}-2-oxoethylidene]amino}oxy)-2-(2H3)methyl(2H3)propanoic acid |
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| Synonym | More Synonyms |
| Description | Aztreonam-d6 is deuterium labeled Aztreonam. Aztreonam (SQ-26,776) is a synthetic monocyclic beta-lactam antibiotic, which has a very high affinity for penicillin-binding protein 3 (PBP-3). |
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| Related Catalog | |
| In Vitro | Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1]. |
| References |
[3]. Guay DR, et al. Aztreonam, a new monobactam antimicrobial. Clin Pharm. 1985 Sep-Oct;4(5):516-26. |
| Density | 1.8±0.1 g/cm3 |
|---|---|
| Melting Point | >210°C |
| Molecular Formula | C13H11D6N5O8S2 |
| Molecular Weight | 441.47 |
| Exact Mass | 441.089508 |
| LogP | -0.66 |
| Index of Refraction | 1.740 |
| Storage condition | 2-8°C |
| 2-({(Z)-[1-(2-Amino-1,3-thiazol-4-yl)-2-{[(2S,3S)-2-methyl-4-oxo-1-sulfo-3-azetidinyl]amino}-2-oxoethylidene]amino}oxy)-2-(2H3)methyl(2H3)propanoic acid |
| Propanoic-3,3,3-d3 acid, 2-[[[(1Z)-1-(2-amino-4-thiazolyl)-2-[[(2S,3S)-2-methyl-4-oxo-1-sulfo-3-azetidinyl]amino]-2-oxoethylidene]amino]oxy]-2-(methyl-d3)- |