Sildenafil-d3

Modify Date: 2024-01-09 20:52:18

Sildenafil-d3 structure	Common Name	Sildenafil-d3
	CAS Number	1126745-90-1	Molecular Weight	477.595
	Density	1.4±0.1 g/cm3	Boiling Point	672.4±65.0 °C at 760 mmHg
	Molecular Formula	C₂₂H₂₇D₃N₆O₄S	Melting Point	N/A
	MSDS	N/A	Flash Point	360.5±34.3 °C

Use of Sildenafil-d3

Sildenafil-d3 is deuterium labeled Sildenafil-d3. Sildenafil (UK-92480) is a potent phosphodiesterase type 5 (PDE5) inhibitor with an IC50 of 5.22 nM.

Name	Sildenafil-d3
Synonym	More Synonyms

Description	Sildenafil-d3 is deuterium labeled Sildenafil-d3. Sildenafil (UK-92480) is a potent phosphodiesterase type 5 (PDE5) inhibitor with an IC50 of 5.22 nM.
Related Catalog	Research Areas >> Cancer Research Areas >> Cardiovascular Disease Signaling Pathways >> Metabolic Enzyme/Protease >> Phosphodiesterase (PDE)
References	[1]. Wang Z, et al. The Selectivity and Potency of the New PDE5 Inhibitor TPN729MA. J Sex Med. 2013 Nov;10(11):2790-7 [2]. [2].Li BB, et al. Sildenafil potentiates the proliferative effect of porcine pulmonary artery smooth muscle cells induced by serotonin in vitro. Chin Med J (Engl). 2011 Sep;124(17):2733-40. [3]. [3]. Moretti R, et al. Sildenafil, a cyclic GMP phosphodiesterase inhibitor, induces microglial modulation after focal ischemia in the neonatal mouse brain. J Neuroinflammation. 2016 Apr 28;13(1):95. [4]. Korkmaz MF, et al. The Effect of Sildenafil on Recuperation from Sciatic Nerve Injury in Rats. Balkan Med J. 2016 Mar;33(2):204-11.

Description

Sildenafil-d3 is deuterium labeled Sildenafil-d3. Sildenafil (UK-92480) is a potent phosphodiesterase type 5 (PDE5) inhibitor with an IC50 of 5.22 nM.

Related Catalog

Research Areas >> Cancer

Research Areas >> Cardiovascular Disease

Signaling Pathways >> Metabolic Enzyme/Protease >> Phosphodiesterase (PDE)

References

[1]. Wang Z, et al. The Selectivity and Potency of the New PDE5 Inhibitor TPN729MA. J Sex Med. 2013 Nov;10(11):2790-7

[2]. [2].Li BB, et al. Sildenafil potentiates the proliferative effect of porcine pulmonary artery smooth muscle cells induced by serotonin in vitro. Chin Med J (Engl). 2011 Sep;124(17):2733-40.

[3]. [3]. Moretti R, et al. Sildenafil, a cyclic GMP phosphodiesterase inhibitor, induces microglial modulation after focal ischemia in the neonatal mouse brain. J Neuroinflammation. 2016 Apr 28;13(1):95.

[4]. Korkmaz MF, et al. The Effect of Sildenafil on Recuperation from Sciatic Nerve Injury in Rats. Balkan Med J. 2016 Mar;33(2):204-11.

Density	1.4±0.1 g/cm3
Boiling Point	672.4±65.0 °C at 760 mmHg
Molecular Formula	C₂₂H₂₇D₃N₆O₄S
Molecular Weight	477.595
Flash Point	360.5±34.3 °C
Exact Mass	477.223755
PSA	121.80000
LogP	2.27
Vapour Pressure	0.0±2.1 mmHg at 25°C
Index of Refraction	1.665

7H-pyrazolo[4,3-d]pyrimidin-7-one, 5-[2-ethoxy-5-[[4-(methyl-d)-1-piperazinyl]sulfonyl]phenyl]-1,6-dihydro-1-methyl-3-propyl-

5-[2-ethoxy-5-[4-(trideuteriomethyl)piperazin-1-yl]sulfonylphenyl]-1-methyl-3-propyl-4H-pyrazolo[4,3-d]pyrimidin-7-one

7H-Pyrazolo[4,3-d]pyrimidin-7-one, 5-[2-ethoxy-5-[[4-(methyl-d)-1-piperazinyl]sulfonyl]phenyl]-1,4-dihydro-1-methyl-3-propyl-

5-(2-Ethoxy-5-{[4-(H)methylpiperazin-1-yl]sulfonyl}phenyl)-1-methyl-3-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one

5-(2-Ethoxy-5-{[4-(H)methyl-1-piperazinyl]sulfonyl}phenyl)-1-methyl-3-propyl-1,4-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one

DC Chemicals Limited
China
Product Name: Sildenafil-d3
Price: ￥Inquiry/1g
Purity: 98.9%
Stocking Period: 1 Day
Contact: Tony Cao

Get all suppliers and price by the below link:

Sildenafil-d3 suppliers

Sildenafil-d3 price

Sildenafil-d3

Use of Sildenafil-d3

Names

Sildenafil-d3 Biological Activity

Chemical & Physical Properties

Synonyms