4-amino-alpha,alpha-dimethyl-1H-imidazo(4,5-c)quinolin-1-ethanol

Modify Date: 2025-08-22 18:16:08

4-amino-alpha,alpha-dimethyl-1H-imidazo(4,5-c)quinolin-1-ethanol Structure
4-amino-alpha,alpha-dimethyl-1H-imidazo(4,5-c)quinolin-1-ethanol structure
 Common Name 4-amino-alpha,alpha-dimethyl-1H-imidazo(4,5-c)quinolin-1-ethanol
CAS Number 112668-45-8 Molecular Weight 256.30300
Density 1.34g/cm3 Boiling Point 513.6ºC at 760 mmHg
Molecular Formula C14H16N4O Melting Point N/A
MSDS N/A Flash Point 264.4ºC

 Names

Name 1-(4-aminoimidazo[4,5-c]quinolin-1-yl)-2-methylpropan-2-ol
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.34g/cm3
Boiling Point 513.6ºC at 760 mmHg
Molecular Formula C14H16N4O
Molecular Weight 256.30300
Flash Point 264.4ºC
Exact Mass 256.13200
PSA 77.69000
LogP 1.86770
Vapour Pressure 2.26E-11mmHg at 25°C
Index of Refraction 1.685

 Synthetic Route

4-chloro-1-(2-hydroxy-2-methylpropyl)-1H-imidazo[4,5-c]-quinoline structure

4-chloro-1-(2-h...

CAS#:129655-65-8

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4-amino-alpha,alpha-dimethyl-1H-imidazo(4,5-c)quinolin-1-ethanol Structure

4-amino-alpha,a...

CAS#:112668-45-8

Literature: Riker Laboratories, Inc. Patent: US4689338 A1, 1987 ; US 4689338 A
α,α-Dimethyl-6H-imidazo [4,5-c]tetrazolo[1,5-a]quinoline-6-ethanol structure

α,α-Dimethyl-6H...

CAS#:200198-35-2

1,2-Dichlorobenzene structure

1,2-Dichlorobenzene

CAS#:95-50-1

~%

4-amino-alpha,alpha-dimethyl-1H-imidazo(4,5-c)quinolin-1-ethanol Structure

4-amino-alpha,a...

CAS#:112668-45-8

Literature: Minnesota Mining and Manufacturing Company Patent: US5741908 A1, 1998 ;
5-(2-aminophenyl)-1-(2-hydroxy-2-methylpropyl)-1H-imidazole-4-carbonitrile structure

5-(2-aminopheny...

CAS#:1375262-91-1

~86%

4-amino-alpha,alpha-dimethyl-1H-imidazo(4,5-c)quinolin-1-ethanol Structure

4-amino-alpha,a...

CAS#:112668-45-8

Literature: Shi, Ce; Xiong, Zhengming; Chittepu, Padmaja; Aldrich, Courtney C.; Ohlfest, John R.; Ferguson, David M. ACS Medicinal Chemistry Letters, 2012 , vol. 3, # 6 p. 501 - 504
1-[(2-chloro-3-nitro-4-quinolinyl)amino]-2-methyl-2-propanol structure

1-[(2-chloro-3-...

CAS#:133860-77-2

~%

4-amino-alpha,alpha-dimethyl-1H-imidazo(4,5-c)quinolin-1-ethanol Structure

4-amino-alpha,a...

CAS#:112668-45-8

Literature: Gerster, John F.; Lindstrom, Kyle J.; Miller, Richard L.; Tomai, Mark A.; Birmachu, Woubalem; Bomersine, Shannon N.; Gibson, Shiela J.; Imbertson, Linda M.; Jacobson, Joel R.; Knafla, Roy T.; Maye, Peter V.; Nikolaides, Nickolas; Oneyemi, Folakemi Y.; Parkhurst, Gwen J.; Pecore, Sharon E.; Reiter, Michael J.; Scribner, Lisa S.; Testerman, Tracy L.; Thompson, Natalie J.; Wagner, Tammy L.; Weeks, Charles E.; Andre, Jean-Denis; Lagain, Daniel; Bastard, Yvon; Lupu, Michel Journal of Medicinal Chemistry, 2005 , vol. 48, # 10 p. 3481 - 3491
4-hydroxy-3-nitro-1H-quinolin-2-one structure

4-hydroxy-3-nit...

CAS#:15151-57-2

~%

4-amino-alpha,alpha-dimethyl-1H-imidazo(4,5-c)quinolin-1-ethanol Structure

4-amino-alpha,a...

CAS#:112668-45-8

Literature: Gerster, John F.; Lindstrom, Kyle J.; Miller, Richard L.; Tomai, Mark A.; Birmachu, Woubalem; Bomersine, Shannon N.; Gibson, Shiela J.; Imbertson, Linda M.; Jacobson, Joel R.; Knafla, Roy T.; Maye, Peter V.; Nikolaides, Nickolas; Oneyemi, Folakemi Y.; Parkhurst, Gwen J.; Pecore, Sharon E.; Reiter, Michael J.; Scribner, Lisa S.; Testerman, Tracy L.; Thompson, Natalie J.; Wagner, Tammy L.; Weeks, Charles E.; Andre, Jean-Denis; Lagain, Daniel; Bastard, Yvon; Lupu, Michel Journal of Medicinal Chemistry, 2005 , vol. 48, # 10 p. 3481 - 3491
2,4-DICHLORO-3-NITRO-QUINOLINE structure

2,4-DICHLORO-3-...

CAS#:132521-66-5

~%

4-amino-alpha,alpha-dimethyl-1H-imidazo(4,5-c)quinolin-1-ethanol Structure

4-amino-alpha,a...

CAS#:112668-45-8

Literature: Gerster, John F.; Lindstrom, Kyle J.; Miller, Richard L.; Tomai, Mark A.; Birmachu, Woubalem; Bomersine, Shannon N.; Gibson, Shiela J.; Imbertson, Linda M.; Jacobson, Joel R.; Knafla, Roy T.; Maye, Peter V.; Nikolaides, Nickolas; Oneyemi, Folakemi Y.; Parkhurst, Gwen J.; Pecore, Sharon E.; Reiter, Michael J.; Scribner, Lisa S.; Testerman, Tracy L.; Thompson, Natalie J.; Wagner, Tammy L.; Weeks, Charles E.; Andre, Jean-Denis; Lagain, Daniel; Bastard, Yvon; Lupu, Michel Journal of Medicinal Chemistry, 2005 , vol. 48, # 10 p. 3481 - 3491
1-[(3-amino-2-chloroquinolin-4-yl)amino]-2-methylpropan-2-ol structure

1-[(3-amino-2-c...

CAS#:133860-78-3

~%

4-amino-alpha,alpha-dimethyl-1H-imidazo(4,5-c)quinolin-1-ethanol Structure

4-amino-alpha,a...

CAS#:112668-45-8

Literature: Gerster, John F.; Lindstrom, Kyle J.; Miller, Richard L.; Tomai, Mark A.; Birmachu, Woubalem; Bomersine, Shannon N.; Gibson, Shiela J.; Imbertson, Linda M.; Jacobson, Joel R.; Knafla, Roy T.; Maye, Peter V.; Nikolaides, Nickolas; Oneyemi, Folakemi Y.; Parkhurst, Gwen J.; Pecore, Sharon E.; Reiter, Michael J.; Scribner, Lisa S.; Testerman, Tracy L.; Thompson, Natalie J.; Wagner, Tammy L.; Weeks, Charles E.; Andre, Jean-Denis; Lagain, Daniel; Bastard, Yvon; Lupu, Michel Journal of Medicinal Chemistry, 2005 , vol. 48, # 10 p. 3481 - 3491
5-amino-1-(2-hydroxy-2-methylpropyl)-1H-imidazole-4-carbonitrile structure

5-amino-1-(2-hy...

CAS#:1375262-89-7

~%

4-amino-alpha,alpha-dimethyl-1H-imidazo(4,5-c)quinolin-1-ethanol Structure

4-amino-alpha,a...

CAS#:112668-45-8

Literature: Shi, Ce; Xiong, Zhengming; Chittepu, Padmaja; Aldrich, Courtney C.; Ohlfest, John R.; Ferguson, David M. ACS Medicinal Chemistry Letters, 2012 , vol. 3, # 6 p. 501 - 504

 Synonyms

4-amino-1-(2-hydroxy-2-methylpropyl)-1H-imidazo[4,5-c]quinoline
2-Hydroxy Imiquimod
R 842
1-(2,hydroxy-2-methylpropyl)-1H-imidazo[4,5-c]quinolin-4-amine
1-(4-amino-1H-imidazo[4,5-c]quinolin-1-yl)-2-methylpropan-2-ol
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Chemsrc provides CAS#:112668-45-8 MSDS, density, melting point, boiling point, structure, etc. Its name is 4-amino-alpha,alpha-dimethyl-1H-imidazo(4,5-c)quinolin-1-ethanol>> amp version: 4-amino-alpha,alpha-dimethyl-1H-imidazo(4,5-c)quinolin-1-ethanol

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