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112668-45-8

112668-45-8 structure
112668-45-8 structure

Name 1-(4-aminoimidazo[4,5-c]quinolin-1-yl)-2-methylpropan-2-ol
Synonyms 4-amino-1-(2-hydroxy-2-methylpropyl)-1H-imidazo[4,5-c]quinoline
2-Hydroxy Imiquimod
R 842
1-(2,hydroxy-2-methylpropyl)-1H-imidazo[4,5-c]quinolin-4-amine
1-(4-amino-1H-imidazo[4,5-c]quinolin-1-yl)-2-methylpropan-2-ol
Density 1.34g/cm3
Boiling Point 513.6ºC at 760 mmHg
Molecular Formula C14H16N4O
Molecular Weight 256.30300
Flash Point 264.4ºC
Exact Mass 256.13200
PSA 77.69000
LogP 1.86770
Vapour Pressure 2.26E-11mmHg at 25°C
Index of Refraction 1.685

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112668-45-8 structure

112668-45-8

Literature: Riker Laboratories, Inc. Patent: US4689338 A1, 1987 ; US 4689338 A

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112668-45-8 structure

112668-45-8

Literature: Minnesota Mining and Manufacturing Company Patent: US5741908 A1, 1998 ;

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112668-45-8 structure

112668-45-8

Literature: Shi, Ce; Xiong, Zhengming; Chittepu, Padmaja; Aldrich, Courtney C.; Ohlfest, John R.; Ferguson, David M. ACS Medicinal Chemistry Letters, 2012 , vol. 3, # 6 p. 501 - 504

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112668-45-8 structure

112668-45-8

Literature: Gerster, John F.; Lindstrom, Kyle J.; Miller, Richard L.; Tomai, Mark A.; Birmachu, Woubalem; Bomersine, Shannon N.; Gibson, Shiela J.; Imbertson, Linda M.; Jacobson, Joel R.; Knafla, Roy T.; Maye, Peter V.; Nikolaides, Nickolas; Oneyemi, Folakemi Y.; Parkhurst, Gwen J.; Pecore, Sharon E.; Reiter, Michael J.; Scribner, Lisa S.; Testerman, Tracy L.; Thompson, Natalie J.; Wagner, Tammy L.; Weeks, Charles E.; Andre, Jean-Denis; Lagain, Daniel; Bastard, Yvon; Lupu, Michel Journal of Medicinal Chemistry, 2005 , vol. 48, # 10 p. 3481 - 3491

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112668-45-8 structure

112668-45-8

Literature: Gerster, John F.; Lindstrom, Kyle J.; Miller, Richard L.; Tomai, Mark A.; Birmachu, Woubalem; Bomersine, Shannon N.; Gibson, Shiela J.; Imbertson, Linda M.; Jacobson, Joel R.; Knafla, Roy T.; Maye, Peter V.; Nikolaides, Nickolas; Oneyemi, Folakemi Y.; Parkhurst, Gwen J.; Pecore, Sharon E.; Reiter, Michael J.; Scribner, Lisa S.; Testerman, Tracy L.; Thompson, Natalie J.; Wagner, Tammy L.; Weeks, Charles E.; Andre, Jean-Denis; Lagain, Daniel; Bastard, Yvon; Lupu, Michel Journal of Medicinal Chemistry, 2005 , vol. 48, # 10 p. 3481 - 3491

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112668-45-8 structure

112668-45-8

Literature: Gerster, John F.; Lindstrom, Kyle J.; Miller, Richard L.; Tomai, Mark A.; Birmachu, Woubalem; Bomersine, Shannon N.; Gibson, Shiela J.; Imbertson, Linda M.; Jacobson, Joel R.; Knafla, Roy T.; Maye, Peter V.; Nikolaides, Nickolas; Oneyemi, Folakemi Y.; Parkhurst, Gwen J.; Pecore, Sharon E.; Reiter, Michael J.; Scribner, Lisa S.; Testerman, Tracy L.; Thompson, Natalie J.; Wagner, Tammy L.; Weeks, Charles E.; Andre, Jean-Denis; Lagain, Daniel; Bastard, Yvon; Lupu, Michel Journal of Medicinal Chemistry, 2005 , vol. 48, # 10 p. 3481 - 3491

~%

112668-45-8 structure

112668-45-8

Literature: Gerster, John F.; Lindstrom, Kyle J.; Miller, Richard L.; Tomai, Mark A.; Birmachu, Woubalem; Bomersine, Shannon N.; Gibson, Shiela J.; Imbertson, Linda M.; Jacobson, Joel R.; Knafla, Roy T.; Maye, Peter V.; Nikolaides, Nickolas; Oneyemi, Folakemi Y.; Parkhurst, Gwen J.; Pecore, Sharon E.; Reiter, Michael J.; Scribner, Lisa S.; Testerman, Tracy L.; Thompson, Natalie J.; Wagner, Tammy L.; Weeks, Charles E.; Andre, Jean-Denis; Lagain, Daniel; Bastard, Yvon; Lupu, Michel Journal of Medicinal Chemistry, 2005 , vol. 48, # 10 p. 3481 - 3491

~%

112668-45-8 structure

112668-45-8

Literature: Shi, Ce; Xiong, Zhengming; Chittepu, Padmaja; Aldrich, Courtney C.; Ohlfest, John R.; Ferguson, David M. ACS Medicinal Chemistry Letters, 2012 , vol. 3, # 6 p. 501 - 504