F3406
Modify Date: 2025-10-06 10:42:51
F3406 structure
|
Common Name | F3406 | ||
|---|---|---|---|---|
| CAS Number | 1115899-15-4 | Molecular Weight | 449.474 | |
| Density | 1.5±0.1 g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C20H21F2N5O3S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of F3406A novel small-molecule arenaviruse inhibitor that exhibits strong anti-LCMV activity (IC50<1 uM) without cell toxicity; inhibits LCMV cell entry by specifically interfering with the pH-dependent fusion in the endosome compartment that is mediated by LCMV glycoprotein GP2; inhibits LCMV multiplication with IC50 of 0.4, 0.7 and 0.9 uM in A549 BHK-21 and Vero cells, respectively. |
| Name | N-(3,5-Difluorophenyl)-2-[5,7-dioxo-6-propyl-2-(1-pyrrolidinyl)-6,7-dihydro[1,3]thiazolo[4,5-d]pyrimidin-4(5H)-yl]acetamide |
|---|---|
| Synonym | More Synonyms |
| Description | A novel small-molecule arenaviruse inhibitor that exhibits strong anti-LCMV activity (IC50<1 uM) without cell toxicity; inhibits LCMV cell entry by specifically interfering with the pH-dependent fusion in the endosome compartment that is mediated by LCMV glycoprotein GP2; inhibits LCMV multiplication with IC50 of 0.4, 0.7 and 0.9 uM in A549 BHK-21 and Vero cells, respectively. |
|---|---|
| References | References 1. Ngo N, et al. J Virol. 2015 Nov;89(21):10924-33. View Related Products by Target Arenavirus |
| Density | 1.5±0.1 g/cm3 |
|---|---|
| Molecular Formula | C20H21F2N5O3S |
| Molecular Weight | 449.474 |
| Exact Mass | 449.133301 |
| LogP | 4.18 |
| Index of Refraction | 1.631 |
| N-(3,5-Difluorophenyl)-2-[5,7-dioxo-6-propyl-2-(1-pyrrolidinyl)-6,7-dihydro[1,3]thiazolo[4,5-d]pyrimidin-4(5H)-yl]acetamide |
| Thiazolo[4,5-d]pyrimidine-4(5H)-acetamide, N-(3,5-difluorophenyl)-6,7-dihydro-5,7-dioxo-6-propyl-2-(1-pyrrolidinyl)- |