bleomycin A5
Modify Date: 2024-01-02 17:53:33
bleomycin A5 structure
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Common Name | bleomycin A5 | ||
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| CAS Number | 11116-32-8 | Molecular Weight | 1440.561 | |
| Density | 1.6±0.1 g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C57H89N19O21S2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of bleomycin A5Bleomycin A5 (Pingyangmycin) is an orally active glycopeptide antibiotics. Bleomycin A5 has a role as an antineoplastic agent, an Apoptosis inducer and a bacterial metabolite[1][2]. |
| Name | bleomycin A5 |
|---|---|
| Synonym | More Synonyms |
| Description | Bleomycin A5 (Pingyangmycin) is an orally active glycopeptide antibiotics. Bleomycin A5 has a role as an antineoplastic agent, an Apoptosis inducer and a bacterial metabolite[1][2]. |
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| Related Catalog | |
| In Vitro | Bleomycin A5 (Pingyangmycin) can inhibit the growth of tumor[1]. |
| In Vivo | Bleomycin A5 (Pingyangmycin) (oral; 18 daily doses of 5 mg/kg) occurs anorexia, cachexia, skin ulcerations, and death and observes interstitial pneumonia, nephrosis and focal necrosis of the adrenal cortex[1]. |
| References |
| Density | 1.6±0.1 g/cm3 |
|---|---|
| Molecular Formula | C57H89N19O21S2 |
| Molecular Weight | 1440.561 |
| Exact Mass | 1439.592163 |
| PSA | 721.60000 |
| LogP | -2.35 |
| Index of Refraction | 1.681 |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
MUTATION DATA
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| N1-(3-((4-Aminobutyl)amino)propyl)bleomycinamide |
| Pingyangmycin A5 |
| (2R,3S,4S,5R,6R)-2-{[(2R,3S,4S,5S,6S)-2-[(1R,2S)-2-[({6-Amino-2-[(1S)-3-amino-1-{[(2S)-2,3-diamino-3-oxopropyl]amino}-3-oxopropyl]-5-methyl-4-pyrimidinyl}carbonyl)amino]-3-{[(2R,3S,4R)-5-{[(2S,3R)-1-({2-[4-({3-[(4-aminobutyl)amino]propyl}carbamoyl)-2,4'-bi-1,3-thiazol-2'-yl]ethyl}amino)-3-hydroxy-1-oxo-2-butanyl]amino}-3-hydroxy-4-methyl-5-oxo-2-pentanyl]amino}-1-(1H-imidazol-4-yl)-3-oxopropoxy]-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H- |
| Zhengguanmycin A5 |
| Bleomycin A5 |
| bleomycetin |
| 2-({2-[2-{[(6-Amino-2-{3-amino-1-[(2,3-diamino-3-oxopropyl)amino]-3-oxopropyl}-5-methyl-4-pyrimidinyl)carbonyl]amino}-3-[(5-{[1-({2-[4-({3-[(4-aminobutyl)amino]propyl}carbamoyl)-2,4'-bi-1,3-thiazol-2'-yl]ethyl}amino)-3-hydroxy-1-oxo-2-butanyl]amino}-3-hydroxy-4-methyl-5-oxo-2-pentanyl)amino]-1-(1H-imidazol-5-yl)-3-oxopropoxy]-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-3-yl}oxy)-3,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-4-yl |
| Bleomycinamide,N1-[3-[(4-aminobutyl)amino]propyl] |