Condurango glycoside A

Modify Date: 2024-01-31 06:56:19

Condurango glycoside A structure	Common Name	Condurango glycoside A
	CAS Number	11051-90-4	Molecular Weight	987.18
	Density	1.28±0.1 g/cm3(Predicted)	Boiling Point	954.0±65.0 °C(Predicted)
	Molecular Formula	C₅₃H₇₈O₁₇	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Condurango glycoside A

Condurango glycoside A is an activator of p53. Condurango glycoside A initiates ROS generation and up-regulates p53 expression. Condurango glycoside A induces apoptosis and pre-mature senescence associated with DNA damage in HeLa cells[1].

Name	[(3S,10S,11S,12S,13S,14S,17S)-17-acetyl-11-acetyloxy-3-[(2S,4S,5R,6R)-5-[(2S,4S,5R,6R)-5-[(2S,3R,4R,5R,6R)-3,5-dihydroxy-4-methoxy-6-methyl-oxan-2-yl]oxy-4-methoxy-6-methyl-oxan-2-yl]oxy-4-methoxy-6-methyl-oxan-2-yl]oxy-14-hydroxy-10,13-dimethyl-1,2,3,4,5,6,7,8,9,11,12,15,16,17-tetradecahydrocyclopenta[a]phenanthren-12-yl] (E)-3-phenylprop-2-enoate

Description	Condurango glycoside A is an activator of p53. Condurango glycoside A initiates ROS generation and up-regulates p53 expression. Condurango glycoside A induces apoptosis and pre-mature senescence associated with DNA damage in HeLa cells[1].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer Signaling Pathways >> Apoptosis >> MDM-2/p53
References	[1]. Bishayee K, et al. Condurango-glycoside-A fraction of Gonolobus condurango induces DNA damage associated senescence and apoptosis via ROS-dependent p53 signalling pathway in HeLa cells. Mol Cell Biochem. 2013 Oct;382(1-2):173-83.

Density	1.28±0.1 g/cm3(Predicted)
Boiling Point	954.0±65.0 °C(Predicted)
Molecular Formula	C₅₃H₇₈O₁₇
Molecular Weight	987.18

Condurango glycoside A

Use of Condurango glycoside A

Names

Condurango glycoside A Biological Activity

Chemical & Physical Properties