Condurango glycoside A

Modify Date: 2025-08-23 09:13:49

Condurango glycoside A Structure
Condurango glycoside A structure
Common Name Condurango glycoside A
CAS Number 11051-90-4 Molecular Weight 987.18
Density 1.28±0.1 g/cm3(Predicted) Boiling Point 954.0±65.0 °C(Predicted)
Molecular Formula C53H78O17 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Condurango glycoside A


Condurango glycoside A is an activator of p53. Condurango glycoside A initiates ROS generation and up-regulates p53 expression. Condurango glycoside A induces apoptosis and pre-mature senescence associated with DNA damage in HeLa cells[1].

 Names

Name [(3S,10S,11S,12S,13S,14S,17S)-17-acetyl-11-acetyloxy-3-[(2S,4S,5R,6R)-5-[(2S,4S,5R,6R)-5-[(2S,3R,4R,5R,6R)-3,5-dihydroxy-4-methoxy-6-methyl-oxan-2-yl]oxy-4-methoxy-6-methyl-oxan-2-yl]oxy-4-methoxy-6-methyl-oxan-2-yl]oxy-14-hydroxy-10,13-dimethyl-1,2,3,4,5,6,7,8,9,11,12,15,16,17-tetradecahydrocyclopenta[a]phenanthren-12-yl] (E)-3-phenylprop-2-enoate

 Condurango glycoside A Biological Activity

Description Condurango glycoside A is an activator of p53. Condurango glycoside A initiates ROS generation and up-regulates p53 expression. Condurango glycoside A induces apoptosis and pre-mature senescence associated with DNA damage in HeLa cells[1].
Related Catalog
References

[1]. Bishayee K, et al. Condurango-glycoside-A fraction of Gonolobus condurango induces DNA damage associated senescence and apoptosis via ROS-dependent p53 signalling pathway in HeLa cells. Mol Cell Biochem. 2013 Oct;382(1-2):173-83.  

 Chemical & Physical Properties

Density 1.28±0.1 g/cm3(Predicted)
Boiling Point 954.0±65.0 °C(Predicted)
Molecular Formula C53H78O17
Molecular Weight 987.18
InChIKey ZKWQLHAAXWFVPF-KNTRCKAVSA-N
SMILES COC1CC(OC2CCC3(C)C(CCC4C3C(OC(C)=O)C(OC(=O)C=Cc3ccccc3)C3(C)C(C(C)=O)CCC43O)C2)OC(C)C1OC1CC(OC)C(OC2OC(C)C(O)C(OC)C2O)C(C)O1
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