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Condurango glycoside A

Names

[ CAS No. ]:
11051-90-4

[ Name ]:
Condurango glycoside A

Biological Activity

[Description]:

Condurango glycoside A is an activator of p53. Condurango glycoside A initiates ROS generation and up-regulates p53 expression. Condurango glycoside A induces apoptosis and pre-mature senescence associated with DNA damage in HeLa cells[1].

[Related Catalog]:

Signaling Pathways >> Apoptosis >> Apoptosis
Research Areas >> Cancer
Signaling Pathways >> Apoptosis >> MDM-2/p53

[References]

[1]. Bishayee K, et al. Condurango-glycoside-A fraction of Gonolobus condurango induces DNA damage associated senescence and apoptosis via ROS-dependent p53 signalling pathway in HeLa cells. Mol Cell Biochem. 2013 Oct;382(1-2):173-83.  

Chemical & Physical Properties

[ Density]:
1.28±0.1 g/cm3(Predicted)

[ Boiling Point ]:
954.0±65.0 °C(Predicted)

[ Molecular Formula ]:
C53H78O17

[ Molecular Weight ]:
987.18


Related Compounds

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