U73975

Modify Date: 2025-08-25 18:50:45

U73975 Structure
U73975 structure
Common Name U73975
CAS Number 110314-48-2 Molecular Weight 502.52000
Density 1.56g/cm3 Boiling Point 766.2ºC at 760mmHg
Molecular Formula C30H22N4O4 Melting Point N/A
MSDS N/A Flash Point 417.2ºC

 Use of U73975


https://pubmed.ncbi.nlm.nih.gov/1624543/

 Names

Name Adozelesin

 U73975 Biological Activity

Description https://pubmed.ncbi.nlm.nih.gov/1624543/
Related Catalog
In Vitro Adolezesin (U73975; 0-50 pg/mL; 90 min) 抑制 ATP 含量,对 SKUT1B、AN3、AE7、HEC1A 和 BG1 的 IC50 分别为 0.097、0.14、0.36、0.53 和 1.65 pg/mL[1]。 Adolezesin (0-50 pg/mL; 0-168 h) 阻断 SKUT1B 细胞 S 期和 G2 期细胞周期[1]。 Cell Cycle Analysis[1] Cell Line: SKUT1B Concentration: 1, 2, 5, 10 and 50 pg/mL Incubation Time: 0-168 h Result: Blocks cell cycle at S and G2 phases at 50 pg/mL in SKUT1B cells.
References

[1]. Nguyen HN, et al. Spectrum of cell-cycle kinetics of alkylating agent adolezesin in gynecological cancer cell lines: correlation with drug-induced cytotoxicity. J Cancer Res Clin Oncol. 1992;118(7):515-22.  

 Chemical & Physical Properties

Density 1.56g/cm3
Boiling Point 766.2ºC at 760mmHg
Molecular Formula C30H22N4O4
Molecular Weight 502.52000
Flash Point 417.2ºC
Exact Mass 502.16400
PSA 111.20000
LogP 5.30770
Index of Refraction 1.816
InChIKey BYRVKDUQDLJUBX-JJCDCTGGSA-N
SMILES Cc1c[nH]c2c1C13CC1CN(C(=O)c1cc4cc(NC(=O)c5cc6ccccc6o5)ccc4[nH]1)C3=CC2=O
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