taurohyodeoxycholic acid sodium salt

Modify Date: 2024-01-02 12:08:34

taurohyodeoxycholic acid sodium salt structure	Common Name	taurohyodeoxycholic acid sodium salt
	CAS Number	110026-03-4	Molecular Weight	540.71
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₆H₄₇NNaO₇S+	Melting Point	168ºC (dec.)(lit.)
	MSDS	Chinese USA	Flash Point	N/A

Use of taurohyodeoxycholic acid sodium salt

Taurodeoxychloic Acid (sodium hydrate) prevents apoptosis by blocking a calcium-mediated apoptotic pathway as well as caspase-12 activation. Taurodeoxychloic Acid (sodium hydrate) is investigated for use in several conditions such as Primary Biliary Cirrhosis (PBC), insulin resistance, amyloidosis, Cystic Fibrosis, Cholestasis, and Amyotrophic Lateral Sclerosis[1].

Name	taurohyodeoxycholic acid sodium salt
Synonym	More Synonyms

Description	Taurodeoxychloic Acid (sodium hydrate) prevents apoptosis by blocking a calcium-mediated apoptotic pathway as well as caspase-12 activation. Taurodeoxychloic Acid (sodium hydrate) is investigated for use in several conditions such as Primary Biliary Cirrhosis (PBC), insulin resistance, amyloidosis, Cystic Fibrosis, Cholestasis, and Amyotrophic Lateral Sclerosis[1].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Signaling Pathways >> Apoptosis >> Caspase Research Areas >> Inflammation/Immunology Research Areas >> Metabolic Disease
Target	Caspase-12
In Vivo	Taurodeoxychloic Acid (TUDCA) is neuroprotective in a transgenic animal model of Huntington’s disease[2].
References	[1]. Xie Q, et al. Effect of tauroursodeoxycholic acid on endoplasmic reticulum stress-induced caspase-12 activation. Hepatology. 2002 Sep;36(3):592-601. [2]. Keene CD, et al. Tauroursodeoxycholic acid, a bile acid, is neuroprotective in a transgenic animal model of Huntington's disease. Proc Natl Acad Sci U S A. 2002 Aug 6;99(16):10671-6.

Melting Point	168ºC (dec.)(lit.)
Molecular Formula	C₂₆H₄₇NNaO₇S+
Molecular Weight	540.71
Exact Mass	521.278687
PSA	135.14000
LogP	4.52640
Storage condition	2-8℃