Antibacterial agent 122
Modify Date: 2025-11-25 08:18:10
Antibacterial agent 122 structure
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Common Name | Antibacterial agent 122 | ||
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| CAS Number | 109310-99-8 | Molecular Weight | 302.35 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C15H14N2O3S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Antibacterial agent 122Antibacterial agent 122 (compound 15) is a thiourea derivative with anti-mycobacterial activity and low cytotoxicity. Antibacterial agent 122 can be used for tuberculosis-related studies[1]. |
| Name | Antibacterial agent 122 |
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| Description | Antibacterial agent 122 (compound 15) is a thiourea derivative with anti-mycobacterial activity and low cytotoxicity. Antibacterial agent 122 can be used for tuberculosis-related studies[1]. |
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| Related Catalog | |
| In Vitro | Antibacterial agent 122 (compound 15) (25-200 µM, 24 h) inhibits M. tuberculosis H37Rv with the MIC50 value of 5.9 µM and inhibits NO production in LPS-stimulated RAW 264.7 cell cultures with an IC50 value of 8.1µM[1]. Antibacterial agent 122 (compound 15) (25-200 µM) acts on NO scavenging with an IC50 value of 184.2 µM, and almost completely inhibits iNOS expression in LPS-stimulated RAW264.7 macrophages at a concentration of 100 µM[1]. Antibacterial agent 122 (compound 15) (0-200 µM, 24 h) inhibits TNF-α and IL-1β production in LPS-stimulated macrophages with the IC50 values of 28.4 µM and 47.9 µM, respectively[1]. Antibacterial agent 122 (compound 15) (25-100 µM, 4 days) inhibits M. tuberculosis M299 with an MIC50 value of 24.7 µM[1]. |
| References |
| Molecular Formula | C15H14N2O3S |
|---|---|
| Molecular Weight | 302.35 |
| InChIKey | QFKSALQTLYBGJU-UHFFFAOYSA-N |
| SMILES | O=C(O)c1ccc(NC(=S)NCc2ccccc2)cc1O |