GSK1614343

Modify Date: 2025-08-27 16:49:45

GSK1614343 Structure
GSK1614343 structure
Common Name GSK1614343
CAS Number 1092476-84-0 Molecular Weight 487.44
Density N/A Boiling Point N/A
Molecular Formula C22H23F6N5O Melting Point N/A
MSDS N/A Flash Point N/A

 Use of GSK1614343


GSK1614343 is the potent antagonist of growth hormone secretagogues type 1a (GHS1a) receptors. GSK1614343 inhibits the calcium response induced by ghrelin with a pIC50 value of 7.90. GSK1614343 represents a useful tool to investigate the physiological relevance of the ghrelin system in rat models[1].

 Names

Name GSK1614343

 GSK1614343 Biological Activity

Description GSK1614343 is the potent antagonist of growth hormone secretagogues type 1a (GHS1a) receptors. GSK1614343 inhibits the calcium response induced by ghrelin with a pIC50 value of 7.90. GSK1614343 represents a useful tool to investigate the physiological relevance of the ghrelin system in rat models[1].
Related Catalog
References

[1]. Perdonà E, et al. Pharmacological characterization of the ghrelin receptor antagonist, GSK1614343 in rat RC-4B/C cells natively expressing GHS type 1a receptors. Eur J Pharmacol. 2011;650(1):178-183.

 Chemical & Physical Properties

Molecular Formula C22H23F6N5O
Molecular Weight 487.44
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