1092476-84-0

1092476-84-0 structure

Name: GSK1614343
Chemical Name: GSK1614343
CAS Number: 1092476-84-0
Molecular Formula: C₂₂H₂₃F₆N₅O
Molecular Weight: 487.44
Catalog: Signaling Pathways GPCR/G Protein GHSR
Create Date: 2022-05-30 20:19:03
Modify Date: 2025-08-27 16:49:45
GSK1614343 is the potent antagonist of growth hormone secretagogues type 1a (GHS1a) receptors. GSK1614343 inhibits the calcium response induced by ghrelin with a pIC50 value of 7.90. GSK1614343 represents a useful tool to investigate the physiological relevance of the ghrelin system in rat models[1].

Name	GSK1614343

Description	GSK1614343 is the potent antagonist of growth hormone secretagogues type 1a (GHS1a) receptors. GSK1614343 inhibits the calcium response induced by ghrelin with a pIC50 value of 7.90. GSK1614343 represents a useful tool to investigate the physiological relevance of the ghrelin system in rat models[1].
Related Catalog	Research Areas >> Metabolic Disease Signaling Pathways >> GPCR/G Protein >> GHSR
References	[1]. Perdonà E, et al. Pharmacological characterization of the ghrelin receptor antagonist, GSK1614343 in rat RC-4B/C cells natively expressing GHS type 1a receptors. Eur J Pharmacol. 2011;650(1):178-183.

Molecular Formula	C₂₂H₂₃F₆N₅O
Molecular Weight	487.44