(rac)-PF-998425

Modify Date: 2025-08-27 10:49:07

(rac)-PF-998425 structure	Common Name	(rac)-PF-998425
	CAS Number	1076225-26-7	Molecular Weight	269.26
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₄H₁₄F₃NO	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of (rac)-PF-998425

(rac)-PF-998425 is a potent, selective, nonsteroidal androgen receptor (AR) antagonist. (rac)-PF-998425 has IC50 values of 26 and 90 nM in the AR binding and cellular assays, respectively. (rac)-PF-998425 has the potential for the research of the androgenetic alopecia[1].

Name	(rac)-PF-998425

Description	(rac)-PF-998425 is a potent, selective, nonsteroidal androgen receptor (AR) antagonist. (rac)-PF-998425 has IC50 values of 26 and 90 nM in the AR binding and cellular assays, respectively. (rac)-PF-998425 has the potential for the research of the androgenetic alopecia[1].
Related Catalog	Research Areas >> Endocrinology Signaling Pathways >> Others >> Androgen Receptor
References	[1]. Li JJ, et al. Rational design and synthesis of 4-((1R,2R)-2-hydroxycyclohexyl)-2(trifluoromethyl)benzonitrile (PF-998425), a novel, nonsteroidal androgen receptor antagonist devoid of phototoxicity for dermatological indications. J Med Chem. 2008;51(21):7010-7014.

Molecular Formula	C₁₄H₁₄F₃NO
Molecular Weight	269.26

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(rac)-PF-998425

Use of (rac)-PF-998425

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(rac)-PF-998425 Biological Activity

Chemical & Physical Properties

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.