(rac)-PF-998425

Modify Date: 2025-08-27 10:49:07

(rac)-PF-998425 Structure
(rac)-PF-998425 structure
Common Name (rac)-PF-998425
CAS Number 1076225-26-7 Molecular Weight 269.26
Density N/A Boiling Point N/A
Molecular Formula C14H14F3NO Melting Point N/A
MSDS N/A Flash Point N/A

 Use of (rac)-PF-998425


(rac)-PF-998425 is a potent, selective, nonsteroidal androgen receptor (AR) antagonist. (rac)-PF-998425 has IC50 values of 26 and 90 nM in the AR binding and cellular assays, respectively. (rac)-PF-998425 has the potential for the research of the androgenetic alopecia[1].

 Names

Name (rac)-PF-998425

 (rac)-PF-998425 Biological Activity

Description (rac)-PF-998425 is a potent, selective, nonsteroidal androgen receptor (AR) antagonist. (rac)-PF-998425 has IC50 values of 26 and 90 nM in the AR binding and cellular assays, respectively. (rac)-PF-998425 has the potential for the research of the androgenetic alopecia[1].
Related Catalog
References

[1]. Li JJ, et al. Rational design and synthesis of 4-((1R,2R)-2-hydroxycyclohexyl)-2(trifluoromethyl)benzonitrile (PF-998425), a novel, nonsteroidal androgen receptor antagonist devoid of phototoxicity for dermatological indications. J Med Chem. 2008;51(21):7010-7014.

 Chemical & Physical Properties

Molecular Formula C14H14F3NO
Molecular Weight 269.26
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